Disease

Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's. However, the protective blood-brain barrier (BBB) makes delivering fluorescent sensors that can detect these small molecules to the brain difficult. Now, researchers demonstrate a way of packaging these sensors for easy passage across the BBB in mice, allowing for improved brain

Two of the closest known relatives to SARS-CoV-2 -- a pair of bat coronaviruses discovered by researchers in Laos -- may transmit poorly in people despite being genetically similar to the COVID-19-causing virus, a new study reveals. The findings provide clues as to why some viruses have greater 'pandemic potential' than others and how researchers

Researchers have identified a potential treatment for the respiratory symptoms of long COVID after discovering an unknown cause of the condition inside the lungs. University of Virginia School of Medicine researchers have identified a potential treatment for the respiratory symptoms of long COVID after discovering an unknown cause of the condition inside the lungs. The

Adults with diabetes who meet the recommended guidelines for physical activity may offset the risk of mortality that is associated with excessive sitting time. Adults with diabetes who meet the recommended guidelines for physical activity may offset the risk of mortality that is associated with excessive sitting time, according to a new study at Columbia

A novel study co-authored by a heart failure cardiologist demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF). A novel study co-authored by a heart failure cardiologist at University Hospitals Harrington Heart & Vascular Institute, demonstrates the effectiveness of a newly developed scoring system

Researchers have developed a model that rapidly converts stem cells to brain cells with protein structures characteristic of Parkinson's disease (PD), enabling the study of the condition's unique and highly variable disease pathology in a petri dish. Researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, have developed

Researchers have identified mouse brain regions vulnerable to blood vessel degeneration, offering clues to the connection between vasculature and neurodegenerative disease. Healthy blood vessels matter for more than just heart health. Vascular well-being is critical for brain health and potentially in addressing age-related cognitive decline and neurodegenerative disorders, like Alzheimer's disease, according to new study

If current guidelines for cholesterol and high blood pressure treatment remain unchanged, a newly unveiled heart risk calculator would render 16 million people ineligible for preventive therapy. Loss of eligibility for cholesterol and blood pressure medicines could lead to 107,000 more heart attacks and strokes over 10 years but may reduce new diabetes cases by

We all know what it's like when the penny suddenly drops. Animals too experience such moments of insight. They could prove useful for research of consciousness. We all know what it's like when the penny suddenly drops. Animals too experience such moments of insight. They could prove useful for research, according to Ekrem Dere. For

A new study explored early-onset dementia in the working-age population in Finland. A new major study by the University of Eastern Finland, the University of Oulu and Neurocenter Finland explored early-onset dementia in the working-age population in Finland. The study cohort was one of the largest in the world to date, and the findings were

Researchers have created a new cortical surface template called 'OpenNeuro Average,' or 'onavg' for short, which provides greater accuracy and efficiency in analyzing neuroimaging data. The human brain is responsible for critical functions, including perception, memory, language, thinking, consciousness, and emotions. To understand how the brain works, scientists often use neuroimaging to record participants' brain

Researchers have found a significant link between the levels of specific dihydroxy fatty acids in umbilical cord blood and ASD symptoms. Their findings highlight the role of these metabolites in the developmental trajectory of ASD and could pave the way for early diagnostic techniques and a better understanding of ASD pathophysiology. Autism spectrum disorder (ASD)