Health

New research highlights middle age as a pivotal period for brain health, with significant changes in how cells remove damaged mitochondria. Defects in this recycling process have been linked to neurodegenerative disorders like Parkinson's and Alzheimer's disease, but until recently it was very challenging to study this process in the aging mammalian brain. Mitochondria, the

The use of biologic and targeted therapies for children with juvenile idiopathic arthritis (JIA) surpassed more typical therapies in recent years, according to researchers. The use of biologic and targeted therapies for children with juvenile idiopathic arthritis (JIA) surpassed more typical therapies in recent years, according to Rutgers Health researchers. Their study, published in Arthritis

Researchers elucidated the molecular details of how Drosophila larval epidermal cells (LECs) undergo cell death in a controlled manner to regulate epithelial tissue remodeling. Specifically, lower activation of the epidermal growth factor receptor (EGFR) signaling pathway occurs following reduced endocytosis. Decreased EGFR pathway activity allows LECs to switch from undergoing single-cell apoptosis to more widespread

An exploratory study has examined metabolomic patterns associated with psychotic-like experiences in adolescents, highlighting the influence of cannabis use. An exploratory study conducted at the University of Eastern Finland has examined metabolomic patterns associated with psychotic-like experiences in adolescents, highlighting the influence of cannabis use. These findings suggest that specific metabolite patterns associated with psychotic-like

An FDA-approved vaccine for smallpox and mpox is effective but causes side effects. The other requires multiple doses. An experimental single-dose vaccine uses the horsepox virus to harness the benefits of both strategies. Vaccines that prevent smallpox and mpox come in 2 varieties. One uses a single shot of a live virus but carries risk

Researchers have developed an optical biosensor that detects the virus that causes mpox. The technology could make diagnosis much faster and cost-effective as the disease continues to spread worldwide. A new variant of human mpox has claimed the lives of approximately 5% of people with reported infections in the Democratic Republic of the Congo since

A team of researchers has developed a technique for diagnosing, managing and treating neurological disorders with minimal surgical risks. A team of researchers led by Rice University's Jacob Robinson and the University of Texas Medical Branch's Peter Kan has developed a technique for diagnosing, managing and treating neurological disorders with minimal surgical risks. The team's

A new study has found highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, offering a new way to kill them. A University of Otago-led study has found highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, offering a new way to kill them. In the study, published in Nature Communications, researchers developed a genetic platform to identify biological

Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to a new editorial. Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to an editorial published in

A new study uncovers vulnerabilities in drug-resistant TB, offering hope for improved treatments. Rutgers Health research has uncovered why a relatively new antibiotic for tuberculosis (TB) works against multidrug-resistant strains, potentially inspiring improved treatments and drug development strategies. The study from scientists at Rutgers New Jersey Medical School and other institutions found that deficiencies in

A new study by medicine safety experts found the use of gabapentinoids -- medicines widely used to treat neuropathic pain -- increased the risk of hip fractures, especially in older patients who were frail or had kidney disease. The study, published today in JAMA Network Open, tracked patients hospitalised for hip fractures in Victoria, Australia

After a comprehensive two-year follow-up, researchers found that MRI-guided stereotactic body radiotherapy (SBRT) for prostate cancer significantly reduced long-term side effects and improved quality of life, particularly in bowel and sexual health, compared to conventional CT-guided treatment. After a comprehensive two-year follow-up, researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that MRI-guided stereotactic