A useful calculator estimates the likelihood of developing epilepsy after a venous stroke. The goal of this tool is to enhance the care provided to those mostly affected, who are mainly young adults.
A useful calculator that estimates the likelihood of developing epilepsy following a venous stroke is detailed in a study conducted by the University of Gothenburg and its collaborators. The goal of this tool is to enhance care for those most impacted, particularly young adults.
A blood clot in the brain’s venous system, known as cerebral venous thrombosis, may lead to a stroke, though it is a rare occurrence. In Sweden, about 150 people are impacted each year, typically women aged between 20 and 50. During the initial phase of the condition, approximately one-third of patients will experience seizures. Determining who is at high risk for recurring seizures and epilepsy is a complex challenge.
Researchers from Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital, in association with fifteen research centers worldwide, have created a practical calculator that swiftly assesses the risk of developing epilepsy at the disease’s onset. The findings from this multi-center study are now published in JAMA Neurology, and the tool is freely accessible.
Crucial for forecasting outcomes
The lead author of the study is Erik Lindgren Bogdanoff, a researcher at the Section of Clinical Neurosciences at Sahlgrenska Academy and a Resident Physician in Neurology at Sahlgrenska University Hospital.
“The calculator assesses the risk of developing epilepsy based on information readily available during a patient’s hospitalization, eliminating the need for extra tests,” he explains, adding:
“For individuals impacted by sinus thrombosis, understanding the potential outcomes is critical. Previously, we have struggled to identify which patients are most likely to experience epilepsy after cerebral venous thrombosis.” If there’s a high projected risk of future seizures, doctors may consider preventive medications during consultations with patients.
Erik Lindgren Bogdanoff points out that while epilepsy can negatively affect quality of life, most individuals with the condition can live normally. However, without appropriate treatment, seizures may become severe enough to necessitate hospitalization. The hope is that this calculator will assist doctors around the globe in making treatment choices or in informing patients about their risks, as well as in guiding future research regarding preventive medical treatments.
Potential to enhance care for young adults
This study draws on registry data from the International Cerebral Venous Thrombosis Consortium (ICVTC) and has been validated by two independent registries: the US ACTION-CVT and the Israeli CVT Study. Overall, data from more than 2,000 individuals were examined.
“The participation of research subjects, along with extensive international collaboration, has been essential in gathering adequate data and conducting studies given the rarity of the disease, leading to results that can be applied in clinical settings. Although the disease is uncommon, it’s vital to improve care for those affected. These findings represent progress toward more personalized care for young people who experience strokes,” concludes Erik Lindgren Bogdanoff.
