Live Coverage of Rams vs. 49ers: Predictions and Viewing Details for Week 15 Thursday Night Football
The NFC West standings are increasingly competitive, and the upcoming “Thursday Night Football” clash between the San Francisco 49ers and the Los Angeles Rams is an essential point in the season.
Despite suffering numerous injuries in 2024, the 49ers (6-7) find themselves surprisingly in contention for the division as they approach Week 15. Along with managing injuries, they’ve faced some off-field issues, such as wide receiver Deebo Samuel expressing a desire for more gameplay involvement, possibly leading to alterations in their offensive strategy with just four games left in the season.
On the other hand, the Rams (7-6) have also encountered their share of injuries which contributed to their uneven performance this season. However, their thrilling 44-42 win against the Bills in Week 14 might signal a shift in momentum for them. Few defensive units are capable of stopping the potent pairing of Cooper Kupp and Puka Nacua, who combined for 254 receiving yards and two touchdowns in that game.
Coaching battles are also notable: Kyle Shanahan has a 10-5 edge over Sean McVay, though McVay’s Rams prevailed in their last encounter, edging out the 49ers 27-24 back in September.
The race for the playoffs is getting intense, with California being the hotbed of one of the most tightly contested divisions in the NFL. YSL News Sports will be providing live updates, highlights, and more for the Week 15 “Thursday Night Football” matchup between the Rams and 49ers.
Start Time for 49ers vs. Rams
- Kickoff: 8:15 p.m. ET (5:15 PT)
- Venue: Levi’s Stadium, Santa Clara, California
The Rams will head north to face the 49ers in their own stadium.
49ers vs. Rams TV Broadcast
- Streaming: Amazon Prime Video
- Broadcast channels: Fox 11 in Los Angeles | Fox 2 in San Francisco
“Thursday Night Football” will be available exclusively on Amazon Prime Video for a nationwide audience.
Fans in the Los Angeles area can catch the game on TV via Fox 11, while viewers in the San Francisco region can go to Fox 2.
Watch “Thursday Night Football” with a Prime Video subscription
Predictions for Rams vs. 49ers
The YSL News Sports team has shared their insights on how the matchup between the Rams and 49ers may unfold:
- Lorenzo Reyes: 49ers 28, Rams 23
- Tyler Dragon: Rams 26, 49ers 21
- Richard Morin: Rams 28, 49ers 27
- Jordan Mendoza: Rams 25, 49ers 24
Live Streaming of 49ers vs. Rams
- Watch live: Amazon Prime Video
Catch “Thursday Night Football” with a Prime Video subscription
Announcers for Thursday Night Football on Amazon Prime Video
Al Michaels will handle play-by-play duties joined by Kirk Herbstreit as the analyst. On the sidelines, Kaylee Hartung will provide updates while Terry McAulay will serve as the rules analyst.
The pregame, halftime, and postgame segments on Prime Video will be hosted by Charissa Thompson, featuring former NFL players such as Ryan Fitzpatrick, Tony Gonzalez, Richard Sherman, and Andrew Whitworth as analysts.
Taylor Rooks will be the featured reporter for Prime Video’s “Thursday Night Football,” and Albert Breer will provide analysis and reports.
Inactive Players for the 49ers Against the Rams
Both Nick Bosa and Dre Greenlaw are active and will play against the Rams. This marks Greenlaw’s first game back after an unusual Achilles injury he sustained during Super Bowl 58 while entering the field.
- QB Joshua Dobbs
- LT Trent Williams
- DL Khalil Davis
- S Malik Mustapha
- RB Israel Abanikanda
- CB Rock Ya-Sin
Inactive Players for the Rams Against the 49ers
- RB Cody Schrader
- LB Brennan Jackson
- OL Dylan McMahon
- OL Warren McClendon Jr.
Odds for Rams vs. 49ers: Spread, Moneyline, and Over/Under
According to BetMGM NFL odds, the 49ers are favored to beat the Rams. If you’re not keen on this game, be sure to explore expert picks and best bets for every NFL game this week.
- Point Spread: 49ers (-2.5)
- Moneyline: 49ers (-150); Rams (+125)
- Over/Under: 48.5
Best Bets for Thursday Night Football
If you want to add more excitement to the “TNF” game, consider these top betting options for tonight’s 49ers-Rams contest. All odds listed are from BetMGM as of Thursday.
- Kyren Williams OVER 73.5 rushing yards (-115);
- Matthew Stafford UNDER 0.5 rushing yards (-120);
- Kyle Juszczyk anytime touchdown (+750)
Update on Isaac Guerendo’s Injury
According to ESPN’s Adam Schefter, Isaac Guerendo intends to participate in Thursday night’s game against the Rams.
He exited the previous Sunday’s victory with an injury that head coach Kyle Shanahan described as It appears there may be a foot sprain. However, Guerendo seemed unconcerned about whether he would be ready for “Thursday Night Football.” After the game, he mentioned to NBC Sports Bay Area that the team was simply exercising caution.
49ers aiming to increase Deebo Samuel’s involvement
The 49ers perform better when they find diverse ways to involve Deebo Samuel, especially with the offense missing key players like Christian McCaffrey and Brandon Aiyuk. Samuel is only the second player in NFL history to achieve both over 4,000 receiving yards and 1,000 rushing yards in his initial five seasons.
If the 49ers hope to triumph over the Rams, escape the bottom of the NFC West, and aim for a late postseason push, Samuel needs to be central to their offensive strategy. This is something the 49ers seem to recognize, particularly after Samuel’s recent social media activity. — Tyler Dragon
Where is the upcoming 49ers vs. Rams game taking place?
The “TNF” clash between the 49ers and Rams will occur at Levi’s Stadium in Santa Clara, California.
Levi’s Stadium opened its doors in 2014 and was the venue for Super Bowl 50, which the Denver Broncos won against the Carolina Panthers. Additionally, it will host Super Bowl 60 on February 8, 2026.
Weather forecast for Rams vs. 49ers
Temperatures at Levi’s Stadium during the game are expected to be in the mid-50s, as per AccuWeather, with a likelihood of rain.
Current NFC West standings
The Seahawks are currently leading the NFC West, but the division remains competitive as the season progresses.
- Seattle Seahawks (8-5)
- Los Angeles Rams (7-6)
- Arizona Cardinals (6-7)
- San Francisco 49ers (6-7)
Who has the NFC West tiebreaker in the division title race?
Los Angeles Rams
The Rams have a clear advantage in their pursuit of the Seahawks. They could potentially complete a head-to-head sweep over the Seahawks, a critical factor in a tiebreaker scenario between two teams. Among the four teams, the Rams have the most remaining games against divisional opponents, giving them an opportunity to enhance their 2-1 record within the division.
Securing four divisional wins would position the Rams favorably in tiebreakers, assuming they defeat the Seahawks in Week 18.
San Francisco 49ers
The 49ers face the toughest challenge to claim the NFC West title.
With only one divisional win, their best-case scenario in the two remaining matchups is to split victories with the Rams and Cardinals, both of which have already defeated the 49ers once this season.
Which NFL teams have the highest number of Super Bowl victories?
The New England Patriots and the Pittsburgh Steelers are tied for the most Super Bowl titles at six each.
The 49ers, boasting eight Super Bowl appearances, have clinched five championships, with their last victory in the 1994 season at Super Bowl XXIX.
The Rams have participated in five Super Bowls, winning two, the most recent being Super Bowl 56 against the Cincinnati Bengals.
Here’s the rundown of NFL franchises with the most Super Bowl wins:
- New England Patriots — 6
- Pittsburgh Steelers — 6
- Dallas Cowboys — 5
- San Francisco 49ers — 5
- Green Bay Packers — 4
- Kansas City Chiefs — 4
- New York Giants — 4
