A team of researchers has confirmed that seven flavonoids derived from food possess antibacterial properties against bacteria responsible for periodontal disease. Their findings indicated that among these compounds, Pru-C12 demonstrated the most significant antimicrobial activity.
Periodontal disease is an inflammatory condition triggered by an infection of pathogenic bacteria in the gums, which can negatively impact both oral and overall health. Maintaining good oral hygiene is crucial for prevention; however, many commercial dental products often serve as disinfectants and can cause irritation. As a result, these products are not ideal for young children and the elderly, who are more vulnerable to periodontal issues.
In search of an easy-to-use antibacterial agent effective for all age groups in preventing periodontal disease, Professor Shigeki Kamitani from Osaka Metropolitan University’s Graduate School of Human Life and Ecology led a study examining the antibacterial properties of seven different compounds. The team specifically tested Prunin laurate (Pru-C12) and similar substances against the periodontal bacteria Porphyromonas gingivalis.
The findings revealed that while several compounds were effective at inhibiting bacterial growth, Pru-C12—derived from natural sources like citrus plants and coconut materials—exhibited the strongest antimicrobial impact.
“Pru-C12 is tasteless and unlikely to cause allergic reactions,” noted Professor Kamitani. “If its safety in humans is confirmed in future studies, it could become a cost-effective antimicrobial option.”