A recent study has demonstrated that 17 common synthetic ‘forever chemicals’ are capable of being absorbed through human skin.
New findings, released in Environment International today, have proven that PFAS (perfluoroalkyl substances) — chemicals known for their resistance to degradation in nature — can breach the skin barrier and enter the bloodstream.
These PFAS are extensively used in various industries and consumer goods due to their water and stain repellent qualities. Despite some being banned, many are still in use with unknown health impacts.
Previously, PFAS were believed to only enter the body through inhalation or ingestion, causing adverse health effects such as immune system suppression and liver issues. However, recent studies suggest a correlation between personal care product usage and PFAS levels in the body, indicating skin absorption.
The new study, led by Dr Oddný Ragnarsdóttir from the University of Birmingham, challenges the notion that PFAS cannot penetrate the skin due to their ionized nature. The research found that skin absorption could be a significant source of exposure to these hazardous chemicals.
Examining 17 PFAS compounds, the team tested their absorption using 3D human skin equivalent models. Most of these substances exhibited substantial dermal absorption, with longer carbon chain compounds showing lower absorption levels compared to shorter chain ones.
Dr Mohamed Abdallah, a co-author of the study, emphasized the importance of investigating a broad range of forever chemicals for exposure risks, rather than a single compound. This insight could be crucial in understanding the potential health risks associated with newer, shorter-chain PFAS variants.
Professor Stuart Harrad, another co-author, highlighted the significance of understanding how easily different chemical structures can be absorbed through the skin. With the industry favoring shorter chain PFAS for perceived lower toxicity, it is essential to assess the risks associated with increased skin absorption.
