Scientists have pointed out the promising role of ultrasound in addressing certain intricate health issues in the human brain.
Although ultrasound was primarily used for imaging, it is rapidly evolving into a targeted treatment option with the potential to significantly change brain health, as noted by the authors of a recent article.
For many years, healthcare professionals globally have relied on ultrasound to monitor fetal development and evaluate the condition of internal organs in patients.
In an article published in the journal PLOS Biology, researchers from Stanford University, the University of Plymouth, and Attune Neurosciences reveal that ultrasound can now non-invasively and accurately target specific regions of the human brain.
This advancement allows them to explore how transcranial ultrasound stimulation (TUS) might assist individuals facing various issues such as pain, alcoholism, obsessive-compulsive disorder (OCD), and Parkinson’s disease, all without relying on medications or surgical procedures.
Additionally, the researchers elaborate on how this technology can be used to temporarily explore areas prior to treatment, functioning as a “search and rescue tool for the brain.”
This approach aids in identifying the origins of brain-related problems before commencing treatment, paving the way for tailored therapies.
Nonetheless, the authors recognize that several intricate challenges must be resolved before TUS can be widely implemented in healthcare facilities—and possibly even at home—around the world.
These challenges include the fact that each of the 8.2 billion brains and skulls globally varies, necessitating further efforts to customize the technique so it can serve a broader population.
While notable advancements in technology have occurred, achieving a balance where it remains both effective and affordable might still take several years.
Currently, the researchers have developed and are testing a TUS device that is compact and straightforward enough for individuals to use at home after undergoing a series of clinical evaluations, removing the need for constant hospital visits.
The article features insights from Dr. Keith Murphy, co-founder of Attune Neurosciences and a researcher at Stanford University School of Medicine, alongside Professor Elsa Fouragnan, who directs the Brain Stimulation Lab at the University of Plymouth’s Brain Research and Imaging Centre.
Dr. Murphy mentions: “There are numerous reasons why people might struggle to reach a clinic, whether due to financial constraints or time limitations. In recent years, we have achieved considerable advancements toward creating a device that utilizes MRI precision yet can also be safely used at home. We have always recognized that portability is a crucial element in making sophisticated brain therapies accessible to everyone, and we’ve made significant progress in demonstrating its effectiveness.”
The researchers also note that focused ultrasound could be combined with other innovative technologies, enhancing the precision and efficacy of systems that facilitate direct communication between the brain and external devices.
Professor Fouragnan stated, “Over many years, we’ve expanded our knowledge of the workings of the brain and the deficiencies that contribute to neurological and mental health disorders. However, while there have been advancements in treatment options, these have not evolved at the same speed. We believe TUS can bridge this gap, and based on our research thus far, we have recognized its potential as a true search and rescue tool for brain health. Clinicians and patients alike are enthusiastic about its possibilities, and if the current pace of progress continues, we could soon have a risk-free technology capable of positively transforming the lives of millions, if not billions, of people.”
