In a randomized clinical trial, giving the clot-busting medication alteplase up to 24 hours after stroke symptoms first appeared increased the odds of better recovery by 50% compared to those who received standard antiplatelet treatment. The clot-dissolving medication, alteplase, improved stroke patients' recovery by more than 50% when given up to 24 hours after the
Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use
In a randomized clinical trial, giving the clot-busting medication alteplase up to 24 hours after stroke symptoms first appeared increased the odds of better recovery by 50% compared to those who received standard antiplatelet treatment. The clot-dissolving medication, alteplase, improved stroke patients' recovery by more than 50% when given up to 24 hours after the
In a randomized clinical trial, giving the clot-busting medication alteplase up to 24 hours after stroke symptoms first appeared increased the odds of better recovery by 50% compared to those who received standard antiplatelet treatment. The clot-dissolving medication, alteplase, improved stroke patients' recovery by more than 50% when given up to 24 hours after the
Scientists have identified genetic components in bats that provide insight into their immune systems. Five years removed from the COVID-19 outbreak, scientists around the world are still studying its effects and, more importantly, ways those effects can be mitigated in the future. An international team of researchers may have just found a critical clue in
Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use
A new, comprehensive map of all the genes essential for blood infections in Plasmodium knowlesi (P. knowlesi), a parasite that causes malaria in humans, has been generated. The map contains the most complete classification of essential genes in any Plasmodiumspecies and can be used to identify druggable parasite targets and mechanisms of drug resistance that
Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life, presumably even in newborns. These changes lead to frequent inflammation and are not affected by drugs targeting the altered mucus production. Despite new medication, cystic fibrosis often leads to
A new AI-based tool can translate a person's thoughts into continuous text, without requiring the person to comprehend spoken words. This latest advance suggests it may be possible, with further refinement, for brain computer interfaces to improve communication in people with aphasia. People with aphasia -- a brain disorder affecting about a million people in
As the U.S. Food and Drug Administration weighs whether to require front-of-package food labels, a new study shows some food labels designed to nudge Americans toward healthier food choices can have the opposite effect. Some food labels designed to nudge Americans toward healthier food choices can have the opposite effect, new University of Florida research
A new study has found that certain bacteria were associated with better memory and attention, while others were linked to an increased risk of Alzheimer's disease. The bacteria in your mouth and on your tongue may be linked to changes in brain function as you age, new research suggested. The study, led by the University
A research team has discovered that the two key pathological hallmarks of Alzheimer's -- tau protein and beta-amyloid -- affect brain circuits in distinct yet synergistic ways, particularly those linked to memory and emotions. The study, using a new animal model of Alzheimer's disease, suggests a potential breakthrough in treatment strategies. Current therapies mainly focus
Scientists have created a new low-cost, fast response sensor to detect lung cancer biomarkers, paving the way for the development of screening devices to spot the disease even before symptoms occur. Similar in design to glucose monitoring devices, the sensor provides results from a blood sample in just 40 minutes. The technology has the potential
A new study of breast cancer survivors has found this psychosocial challenge impacts almost every important domain of their lives -- the emotional, behavioral, cognitive, relational and professional. A larger number of domains was affected, and they were affected more frequently in those with greater fear of recurrence. The majority of study participants indicated that
Researchers have unveiled the precise brain mechanisms that enable animals to overcome instinctive fears. The study in mice could have implications for developing therapeutics for fear-related disorders such as phobias, anxiety and post-traumatic stress disorder (PTSD). Researchers at the Sainsbury Wellcome Centre (SWC) at UCL have unveiled the precise brain mechanisms that enable animals to
Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery. Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system -- a group of proteins that patrols our body
Research in fruit flies has identified specific groups of cholinergic brain cells that are involved in alcohol-induced insomnia. This work could ultimately lead to targeted treatments for alcohol-related sleep loss, helping people recover from alcohol use disorder. Alcohol use disorder, which affects over 10% of Americans, can lead to persistent and serious insomnia. Difficulties falling
The research found that heavy drinkers with either diabetes, high blood pressure or a high waist circumference are as much as 2.4 times more likely to develop advanced liver disease. Why do some people who consume a few glasses of alcohol a day develop advanced liver disease while others who drink the same amount don't?
