Disease

Research found the choroid plexus and cerebrospinal fluid play a key role in maintaining a pool of newly born neurons to repair the adult brain after injury. University of Cincinnati researchers have pioneered an animal model that sheds light on the role an understudied organ in the brain has in repairing damage caused by stroke.

By prohibiting the Activin A protein from functioning, researchers were able to halt the development of dyskinesia symptoms and effectively erase the brain's 'bad memory' response to L-DOPA treatments. Common treatments for Parkinson's disease can address short-term symptoms but can also cause extensive problems for patients in the long run. Namely, treatments can cause dyskinesia

CAR-T cell therapy helps some with intractable lymphoma, but those who relapse have few options. Modifying the therapy's molecular target improved response. CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement

Cystic fibrosis is a hereditary disease that so far has been incurable. Those affected have thick, viscous mucus secretions in their lungs, and lung function diminishes steadily over time. Today, triple combination therapy makes it possible to address the root causes of the defect underlying the disease. This form of treatment was recently approved for

A major clinical trial has shown the Lee Silverman Voice Treatment (LSVT LOUD ) is more effective than the current speech and language therapy commonly provided, when treating patients with Parkinson's disease (PD). A major clinical trial, led by experts at the University of Nottingham, has shown the Lee Silverman Voice Treatment (LSVT LOUD®) is

A new study looks at predicting how quickly people with early Alzheimer's disease will experience cognitive decline. The study also looked at how the new drugs recently approved for the disease may reduce decline. A new study looks at predicting how quickly people with early Alzheimer's disease will experience cognitive decline. The study is published

Researchers have built the first-ever molecular atlas of the human brain vasculature at single-cell resolution, spanning from early development to adulthood and through disease stages such as brain tumors and brain vascular malformations. An international consortium of researchers led by University Health Network (UHN) in Toronto and University of Zurich have built the first-ever molecular

In preclinical studies, a team of researchers report new findings on a therapeutic combination that regenerated human insulin-producing beta cells, providing a possible new treatment for diabetes. In preclinical studies, a team of researchers from Mount Sinai Health System in New York City and City of Hope in Los Angeles report new findings on a

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection. Now, researchers have developed a gene-editing approach that efficiently corrects the most common mutation that causes cystic fibrosis, found in 85 percent of patients. With further development, it

In a study involving 50,000+ individuals from around the world, higher gut levels of Blastocystis, a single-celled organism commonly found in the digestive system, were linked to more favorable indicators of health. In an analysis of more than 50,000 individuals from around the world, carriers of gut Blastocystis, a single-celled organism that has been labeled

A longitudinal study has found that high-intensity interval exercise improves brain function in older adults for up to 5 years. A longitudinal study by University of Queensland researchers has found high-intensity interval exercise improves brain function in older adults for up to 5 years. Emeritus Professor Perry Bartlett and Dr Daniel Blackmore from UQ's Queensland

Unique recordings show that bats can ramp up heart rate from 6 to 900 b.p.m within minutes Researchers from Konstanz have measured the heart rate of bats over several days in the wild, including complete flights -- the first time this has been done for a bat species. To record the heart rate of male