Disease

Researchers identified a novel compound aimed at improving the treatment of opioid overdoses. Scientists at the University of Florida have identified a novel compound aimed at improving the treatment of opioid overdoses, which claimed the lives of more than 81,000 Americans last year. The discovery could combat the devastating epidemic of opioid-related deaths, driven predominantly

New research has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing effective pain relief. New research led by UCLA Health has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing

Researchers outline some of the intermediate biological steps that could play into how prenatal cannabis exposure leads to behavioral issues down the line. Scientists are trying to understand how cannabis may affect long term neurodevelopment when people were exposed to it in the womb. Previous work by WashU researchers Sarah Paul and David Baranger in

New research details the connection between the neurological symptoms associated with aura and the migraine that follows. The study also identifies new proteins that could be responsible for headaches and may serve as foundation for new migraine drugs. New research describes for the first time how a spreading wave of disruption and the flow of

Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed. But now, researchers have found a way to identify the condition while patients are still alive. Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists. A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in

Why do employees sometimes accept working for an abusive boss? A new study suggests that when a leader is seen as a high performer, employees are more likely to label abuse as just 'tough love.' Why do employees sometimes accept working for an abusive boss? A new study suggests that when a leader is seen

Post-COVID research has extensively focused on the efficacy of internal travel restrictions and cross-border travel has received less attention due to challenges in accessing quality data. In a major multidisciplinary collaboration effort across Finland, Sweden, Norway, and Denmark, a group of researchers -- including mathematicians, physicists and computer scientists -- have published a pioneering study

In a new paper, researchers and citizen mycologists describe the two new species as Psilocybe ingeli and Psilocybe maluti. The paper also contains information on the traditional use of P. maluti by Basotho traditional healers from the mountain kingdom of Lesotho. According to the researchers, this appears to be the only recorded first-hand report of

Research finds that booster doses of bivalent vaccines given every three to six months helps maintain a person's ability to neutralize multiple SARS-CoV-2 strains, including XBB.1.5 People who have received solid organ transplants and take immunosuppressant medications to prevent rejection are among those most susceptible to the damaging effects of COVID-19, including breakthrough infections, severe

Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy. Researchers have now discovered how the cortisone compound influences the impaired inflammatory response and which patients benefit from it. Their method uses so-called single-cell analyses and raises hopes for a precise prediction tool

Researchers found found that as people's arousal levels dwindle during an fMRI, such as if they become more relaxed and sleepy, resulting changes in breathing and heart rates alter blood oxygen levels in the brain, which are then falsely detected on the scan as neuronal activity. The researchers then developed a method, called RIPTiDe, to