Parkinson

Researchers have developed a model that rapidly converts stem cells to brain cells with protein structures characteristic of Parkinson's disease (PD), enabling the study of the condition's unique and highly variable disease pathology in a petri dish. Researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, have developed

People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to new research. The study also found that people with a high level of muscle strength were less likely to

Researchers have discovered two proteins that act as regulators for mitophagy. The discovery opens a new avenue for researchers to boost mitophagy activity, to promote mitochondrial and neuronal health. Researchers at WEHI in collaboration with a team at the University of Vienna have discovered two proteins that act as regulators for mitophagy. Mitophagy is the

A new preclinical model offers a unique platform for studying the Parkinson's disease process and suggests a relatively easy method for detecting the disease in people. A new preclinical model offers a unique platform for studying the Parkinson's disease process and suggests a relatively easy method for detecting the disease in people, according to a

An automated assessment technique that uses artificial intelligence could revolutionize the management of Parkinson's disease. A video-processing technique developed at the University of Florida that uses artificial intelligence will help neurologists better track the progression of Parkinson's disease in patients, ultimately enhancing their care and quality of life. The system, developed by Diego Guarin, Ph.D.

The largest study of CTE to date has found a new link between playing contact sports, chronic traumatic encephalopathy (CTE), and the development of a movement disorder known as parkinsonism. The largest study of CTE to date has found a new link between playing contact sports, chronic traumatic encephalopathy (CTE), and the development of a

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets may help to dissolve aggregated protein. The study deepens our understanding of neurodegenerative diseases linked to protein aggregation and could help develop new therapies. Liquid-liquid phase separation

By prohibiting the Activin A protein from functioning, researchers were able to halt the development of dyskinesia symptoms and effectively erase the brain's 'bad memory' response to L-DOPA treatments. Common treatments for Parkinson's disease can address short-term symptoms but can also cause extensive problems for patients in the long run. Namely, treatments can cause dyskinesia

A major clinical trial has shown the Lee Silverman Voice Treatment (LSVT LOUD ) is more effective than the current speech and language therapy commonly provided, when treating patients with Parkinson's disease (PD). A major clinical trial, led by experts at the University of Nottingham, has shown the Lee Silverman Voice Treatment (LSVT LOUD®) is

Years before the onset of symptoms. This groundbreaking test offers early detection and potential intervention, revolutionizing how we approach Parkinson's disease. With its use of AI and simple blood sample, this innovation is a game-changer in the field of Parkinson's research, offering hope for early diagnosis and treatment

Harmful substances into the body. This new finding could lead to potential therapeutic interventions for Parkinson's disease by targeting the gut microbiota. The study's implications are significant as it brings us closer to understanding the role of the gut-brain axis in neurological disorders

That drives the spread of Parkinson's disease-causing alpha-synuclein. This discovery offers promising potential for developing targeted therapies to halt the progression of Parkinson's disease. The identification of Aplp1 as a key player in the spread of alpha-synuclein provides a unique opportunity for new treatment approaches, marking a significant advancement in the understanding and potential treatment of Parkinson's disease. The research findings provide hope for the development of more effective and targeted therapies, bringing us one step closer to finding a cure for this devastating neurodegenerative disease