Health

As rates of obesity, as defined by body mass index (BMI), continue to climb in the United States, so have efforts to lose weight, including a new era of weight-loss drugs. Yet a new systematic review and meta-analysis found that cardiorespiratory fitness was a stronger predictor of both cardiovascular disease and all-cause mortality than BMI.

Salk scientists have tracked the flow of trans fats using mouse models to describe the molecular mechanisms that cause trans fats to promote atherosclerotic cardiovascular disease (ASCVD), explaining how industrially produced trans-unsaturated fatty acids in our food significantly promote ASCVD and encouraging lawmakers to impose regulations on the use of these fats in food. This

A quick finger prick and a few drops of blood on a card that can be sent in regular mail. This approach could soon make Alzheimer's testing much more accessible worldwide. A quick finger prick and a few drops of blood on a card that can be sent in regular mail. This approach could soon

A commonly prescribed medication for heart failure was linked to a lower risk of heart damage, or cardiotoxicity, among high-risk cancer patients undergoing chemotherapy treatment using anthracyclines, according to recent research. A commonly prescribed medication for heart failure was linked to a lower risk of heart damage, or cardiotoxicity, among high-risk cancer patients undergoing chemotherapy

Engaging in everyday physical activity has immediate benefits for brain health. Middle-aged people who participated in everyday movement showed improvement in cognitive processing speed equivalent to being four years younger, regardless of the activity's intensity. Exercise has been shown to improve brain health and reduce the risk of cognitive decline and dementia over the long-term.

New research has found that people with a genetic defect in their ability to digest sucrose eat less cake, sweets and chocolate, which could hold the key to helping the wider population to eat less sugar. The international study shows that genetic variations in the sucrase-isomaltase (SI) gene are associated with the intake, and preference

Children living in war-torn countries not only suffer from poor mental health outcomes, but war may cause adverse biological changes at the DNA level, which could have lifelong health impacts, according to a ground-breaking study. Children living in war-torn countries not only suffer from poor mental health outcomes, but war may cause adverse biological changes

Scientists have identified human antibodies capable of targeting the proteins responsible for severe malaria, potentially paving the way for new vaccines or treatments. Using organ-on-a-chip technology, researchers successfully demonstrated that these antibodies prevent infected red blood cells from adhering to vessel walls, a key driver of severe malaria symptoms. The antibodies neutralize a conserved region

Researchers shrink gastrointestinal tumors in mice using a yeast probiotic to deliver immunotherapy to the gut, offering a potentially novel strategy to target hard-to-reach gut cancers. Immunotherapy is a promising treatment that recruits the immune system to help fight cancer, but it has had limited success in gastrointestinal cancers. Now, researchers at Washington University School

People around the world associate a trilled R sound with a rough texture and a jagged shape, and an L sound with smooth texture and a flat shape, according to the findings of a new study. Researchers believe this association may be more universal than the famous bouba/kiki effect. People around the world associate a

A new study finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods. The study discovered that at least 3% of normal cells from

Researchers have pinpointed what could be the early genetic origins of breast cancer -- cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators analyzed the genomes of more than 48,000 individual breast cells from women without cancer, using novel techniques for decoding the genes of single cells. While