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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to

Revolutionizing Drug Screening: The Power of Electrical Impedance Tomography for Extracellular Voltage Activation

Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving

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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to

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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to

Revolutionary Nanosensing Method Enhances Quality Control of Viral Vectors in Gene Therapy

Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can

Revolutionizing Drug Screening: The Power of Electrical Impedance Tomography for Extracellular Voltage Activation

Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
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Uncovering Dengue’s Invasion Strategies: How This Virus Spreads and What You Can Do

Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential

Blood Proteins: Key Indicators for Predicting Over 60 Diseases – Unlocking Health Insights

The researchers report the ability of protein 'signatures' to predict the onset of 67 diseases including multiple myeloma, non-Hodgkin lymphoma, motor neurone disease, pulmonary fibrosis, and dilated cardiomyopathy. Protein 'signatures', which can be obtained via a blood sample, can be used to predict the onset of 67 diseases including multiple myeloma, non-Hodgkin lymphoma, motor neurone

How Evolution Tamed a Deadly Virus: Insights and Ongoing Concerns

Over the last century, a once-deadly mosquito-borne virus has evolved so that it no longer sickens humans. New research shows that changes in the virus's ability to target human cells paralleled the decline in illness and death. The findings offer important lessons in virology that may help guide better preparedness for future outbreaks of other

Discover How a Human-Infecting Parasite Creates Sterile Soldiers Like Ants and Termites

New research finds a tiny freshwater parasite known to cause health problems in humans defends its colonies with a class of soldiers that cannot reproduce. The discovery vaults this species of parasitic flatworm into the ranks of complex animal societies such as ants, bees and termites, which also have distinct classes of workers and soldiers

How Body Composition Influences Dementia and Parkinson’s Risk: Key Insights

People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to new research. The study also found that people with a high level of muscle strength were less likely to

Do Wearable Devices Impact Health Negatively? Exploring the Risks and Benefits

For patients with Afib, using a wearable device can lead to higher rates of anxiety about their Afib symptoms and treatment, doctor visits, and use of informal healthcare resources, according to a new study. Using a wearable device, such as a smart watch, to track health data and symptoms, is supposed to help people monitor

How the COVID-19 Pandemic Hindered Progress on Health-Related Sustainable Development Goals and Worsened Inequalities

The COVID-19 pandemic significantly widened existing economic and health disparities between wealthy and low-income countries and slowed progress toward health-related Sustainable Development Goals (SDGs), according to a new study. The COVID-19 pandemic significantly widened existing economic and health disparities between wealthy and low-income countries and slowed progress toward health-related Sustainable Development Goals (SDGs), according to

BePRECISE Consortium Releases Essential Guidelines to Improve Precision Medicine Research Reporting

The inaugural reporting guidelines for precision medicine research have just been published. The paper from the BePRECISE consortium describes comprehensive guidelines aimed at improving the accuracy, safety, and health equity in precision medicine. BePRECISE is Better Precision-data Reporting of Evidence from Clinical Intervention Studies & Epidemiology. Chair of the Guidelines committee, Professor Paul Franks, Lund

Gene Misbehavior: Uncovering Its Widespread Impact in Healthy Individuals

New insights into the prevalence and mechanisms of gene misexpression in a healthy population could help in diagnosing and developing treatments for complex diseases. Scientists have uncovered that 'gene misbehaviour' -- where genes are active when they were expected to be switched off -- is a surprisingly common phenomenon in the healthy human population. The

The Influence of Receptor Density on Daily Rhythms in the Biological Clock

Tweaking the numbers of receptors in a key brain area changes the daily rhythms of rest and wake in mice. In humans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life. They help the body to prepare for expected changes in the environment and

Optimal Age for Olympic Athletes: Discover When They Peak Performance

There's a lot that goes into an Olympic athlete's quest for gold -- years of training and rigor -- but also, an athlete's age. A team used statistics to figure out when an Olympic track-and-field athletes' peak performance will be. There's a lot that goes into an Olympic athlete's quest for gold -- years of

COVID-19 vs. Other Illnesses: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Prevalence Research Findings

Rates of subsequent myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) following an acute illness were roughly the same between people whose acute illness was due to COVID-19 and those who did not have COVID-19, a new study finds. A new study led by UCLA finds that rates of subsequent myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) following an acute