Disease

A canine gallbladder disease that involves the accumulation of abnormal mucus similar to that seen in human cystic fibrosis (CF) patients is caused by improper expression of the gene associated with CF in humans. The finding could have implications for human CF patients as well as for animal models of CF. A canine gallbladder disease

Researchers reveal the impact of transthyretin protein levels on heart disease risk. Physician-scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine have uncovered significant findings regarding the impact of transthyretin, or TTR, protein levels on heart disease risk. The study, recently published in Nature Communications, explores how variations in TTR

SARS-CoV-2, the virus responsible for COVID-19, is widespread among wildlife species, according to new research. The virus was detected in six common backyard species, and antibodies indicating prior exposure to the virus were found in five species, with rates of exposure ranging from 40 to 60 percent depending on the species. SARS-CoV-2, the virus responsible

Researchers have created a new cortical surface template called 'OpenNeuro Average,' or 'onavg' for short, which provides greater accuracy and efficiency in analyzing neuroimaging data. The human brain is responsible for critical functions, including perception, memory, language, thinking, consciousness, and emotions. To understand how the brain works, scientists often use neuroimaging to record participants' brain

Researchers have found a significant link between the levels of specific dihydroxy fatty acids in umbilical cord blood and ASD symptoms. Their findings highlight the role of these metabolites in the developmental trajectory of ASD and could pave the way for early diagnostic techniques and a better understanding of ASD pathophysiology. Autism spectrum disorder (ASD)

Research shows that the physical activities we do as we go about our lives, at work or in the home, aren't enough to protect us from having a stroke. However, exercising in our free time and using active modes of transport are associated with a decreased risk of stroke. Research conducted at the University of

Losing someone close, like a family member, can make you age faster. The study found that people who lost a parent, partner, sibling, or child, showed signs of older biological age compared to those who hadn't experienced such losses. Losing someone close, like a family member, can make you age faster, says a new study

Scientists have developed the R-EDByUS score, a new model predicting neurological outcomes in out-of-hospital cardiac arrest patients using prehospital data only. The model allows for rapid decision-making upon hospital arrival, enhancing patient care and resource allocation. This innovation marks a significant advancement in emergency medical treatment. When it comes to treating cardiac arrest, acting quickly

A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease

The processes in the brain and body through which physical exercise reduces depressive symptoms have been explored. The processes in the brain and body through which physical exercise reduces depressive symptoms have been explored by UCL researchers. Depression is the leading cause of disability worldwide and is associated with disruptions to several brain and psychological

Researchers uncovered new information about the role inflammation plays in mitigating liver fibrosis, which is associated with metabolic-associated fatty liver disease (MAFLD), one of the most common diseases in the world affecting up to 40 percent of U.S. adults. Researchers at UCLA Health uncovered new information about the role inflammation plays in mitigating liver fibrosis

A new paper surveying advances in diabetes pathogenesis and treatment explores the complex factors contributing to the onset and progression of the disease, suggesting that an understanding of these dynamics is key to developing targeted interventions to reduce the risk of developing diabetes and managing its complications. A new paper surveying advances in diabetes pathogenesis