Disease

Scientists created new tools to study brain messenger proteins called neuropeptides in the brains of behaving animals, discovering they are the primary messengers in the fear circuit in mouse brains, and that multiple neuropeptides work together to achieve this--explaining why some clinical trials that target just one neuropeptide have failed. The new tools and findings

Surgeons compared traditional and new fully hydroxyapatite-coated hip replacement stems. They found the new stems offer larger contact areas, while traditional ones preserve bone density long-term. This insight aims to improve patient outcomes and reduce revision surgeries. Needing a hip replacement is unfortunate, but even more unfortunate is to need to do it again. Surgeons

The shape of a person's kneecap could be an indicator of whether they're more at risk of developing osteoarthritis, according to a new study. The shape of a person's kneecap could be an indicator of whether they're more at risk of developing osteoarthritis, according to a new study from The Australian National University (ANU). According

Long-acting injectable cabotegravir (CAB-LA) was safe and well tolerated as HIV pre-exposure prophylaxis (PrEP) before and during pregnancy in the follow-up phase of a global study among cisgender women. Long-acting injectable cabotegravir (CAB-LA) was safe and well tolerated as HIV pre-exposure prophylaxis (PrEP) before and during pregnancy in the follow-up phase of a global study

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research. A simple blood test that measures the number of lymphocytes, a type of white blood

People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to new research. The study also found that people with a high level of muscle strength were less likely to

People who speak a language that has multiple words for different shades of colour perceive the shades more quickly. Bees have a phenomenal ability to perceive different shades of colour, and their eyes are able to see ultraviolet light. This helps them find flowers that produce nectar. Human beings are also influenced by colours and

The COVID-19 pandemic significantly widened existing economic and health disparities between wealthy and low-income countries and slowed progress toward health-related Sustainable Development Goals (SDGs), according to a new study. The COVID-19 pandemic significantly widened existing economic and health disparities between wealthy and low-income countries and slowed progress toward health-related Sustainable Development Goals (SDGs), according to

Researchers offer the first comprehensive ranking of the relative role and significance of every known gene and protein in the development of Alzheimer's Disease. Researchers at The Jackson Laboratory offer the first comprehensive ranking of the relative role and significance of every known gene and protein in the development of Alzheimer's Disease in advance of

Researchers conducted a breakthrough proof-of-concept study that found an HIV-like virus particle that could cease the need for lifelong medications. Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease

In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy. Increasing ketone supply to the heart in mice with heart failure with preserved ejection fraction (HFpEF) allowed their hearts to utilize more ketones and produce more energy, according

Current medical guidelines recommend that people in a preliminary stage of type 2 diabetes lose at least 7 percent of their body weight in order to prevent manifest diabetes. Diabetes experts advocate glycemic remission (normalization of blood sugar regulation) as a prevention goal for people with prediabetes or a high risk of type 2 diabetes.