Disease

Researchers have discovered a novel pain control pathway that links the cingulate cortex in the front of the brain, through the pons region of the brainstem, to cerebellum in the back of the brain. The placebo effect is very real. This we've known for decades, as seen in real-life observations and the best double-blinded randomized

Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research. Mice don't get Alzheimer's -- and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments. Now, researchers at The

Researchers offer the first comprehensive ranking of the relative role and significance of every known gene and protein in the development of Alzheimer's Disease. Researchers at The Jackson Laboratory offer the first comprehensive ranking of the relative role and significance of every known gene and protein in the development of Alzheimer's Disease in advance of

Researchers conducted a breakthrough proof-of-concept study that found an HIV-like virus particle that could cease the need for lifelong medications. Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease

Personalized text messages effectively promoted increased physical activity for patients after significant heart events -- such as a heart attack or surgery -- but those effects later diminished. Researcher say the results show incredible promise for simple, low cost interventions delivered through mobile technology and their potential to help prevent secondary cardiovascular events in patients.

Whether or not a person becomes seriously ill with COVID-19 depends, among other things, on genetic factors. With this in mind, researchers investigated a particularly large group of affected individuals. They confirmed the central and already known role of the TLR7 gene in severe courses of the disease in men, but were also able to

Rates of subsequent myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) following an acute illness were roughly the same between people whose acute illness was due to COVID-19 and those who did not have COVID-19, a new study finds. A new study led by UCLA finds that rates of subsequent myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) following an acute

Genomics and lab studies reveal numerous findings, including a key role for Reelin amid neuronal vulnerability, and for choline and antioxidants in sustaining cognition. An MIT study published today in Nature provides new evidence for how specific cells and circuits become vulnerable in Alzheimer's disease, and hones in on other factors that may help some

Resulting atlas of the aging human brain holds molecular insights into the brain's vulnerability and resilience. Less than a decade ago, when Dr. Hansruedi Mathys launched an ambitious project to create an annotated library of all the gene readouts stored within 100 individual brain cells, the task felt daunting. Now, with technological advances, Mathys successfully

A new study provides evidence that a spillover of avian influenza from birds to dairy cattle across several U.S. states has now led to mammal-to-mammal transmission -- between cows and from cows to cats and a raccoon. A new Cornell University study provides evidence that a spillover of avian influenza from birds to dairy cattle

Researchers have discovered two proteins that act as regulators for mitophagy. The discovery opens a new avenue for researchers to boost mitophagy activity, to promote mitochondrial and neuronal health. Researchers at WEHI in collaboration with a team at the University of Vienna have discovered two proteins that act as regulators for mitophagy. Mitophagy is the

Adolescents with severe obesity who received meal-replacement therapy plus financial incentives experienced a greater reduction in body mass index compared to those who received meal replacement therapy alone, according to recent findings. Adolescents with severe obesity who received meal-replacement therapy plus financial incentives experienced a greater reduction in body mass index compared to those who