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Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving

Fewer side effects, improved chances of healing: the goal of precision medicine is to provide patients with the most individualized treatment possible. This requires a precise understanding of what is happening at the cellular level. Researchers have now succeeded in mapping the interactions of 144 active substances with around 8,000 proteins. The results could help

Companies and institutes are currently working on biotechnological processes for the production of 'dairy products' without the use of cows: In so-called precision fermentation, egg and milk proteins are produced with the help of bacteria, yeasts or other fungi. This results in foods such as milk or cheese with a familiar flavor and texture. Supporters

A new small study has revealed the impact of obesity on muscle structure in patients having a form of heart failure called heart failure with a preserved ejection fraction (HFpEF). A new small study led by Johns Hopkins Medicine researchers and published July 25th in the journal Nature Cardiovascular Research has revealed the impact of

Highly localized TB strains are less infectious in cosmopolitan cities and more likely to infect people from the geographic area that is the strain's natural habitat. The research provides the first controlled evidence that TB strains may evolve with their human hosts, adapting to be more infectious to specific populations. The findings offer new clues

Food in hospitals often does not enjoy a good reputation. The proportion of meat on the plate in particular is too high. Clinics can do a lot to motivate patients to choose a healthier menu, as two new studies show. Food in hospitals often does not enjoy a good reputation. The proportion of meat on

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to

Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can

Researchers have developed a formula and easy-to-use assessment tool for estimating fall risks using a database of older adults. Preventing falls among older adults is expected to extend life expectancy and reduce medical and nursing care costs. An aging society has posed a new global problem, the risk of falling. It is estimated that 1

New research suggests that an El Nino event may have aided the establishment and spread of a novel cholera strain during an early 20th-century pandemic, supporting the idea that climate anomalies could create opportunities for the emergence of new cholera strains. New research suggests that an El Niño event may have aided the establishment and

Researchers offer a new perspective on antifragility, proposing a unified framework for understanding the property across different complex systems. Researchers constantly seek innovative approaches to tackle cancer. One concept gaining traction is antifragility, a property where systems not only withstand stress but improve because of it. In cancer research, this concept is particularly relevant for

An artificial intelligence method to detect biomarkers in tumor biopsies promises to cut weeks and thousands of dollars from cancer detection, extending the benefits of precision oncology to underserved and under-resourced patients. A new generation of artificial intelligence (AI) tools designed to allow rapid, low-cost detection of clinically actionable genomic alterations directly from tumor biopsy