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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to
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Revolutionary Nanosensing Method Enhances Quality Control of Viral Vectors in Gene Therapy

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Revolutionizing Drug Screening: The Power of Electrical Impedance Tomography for Extracellular Voltage Activation

Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
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Unlocking Precision Medicine: The Hidden Impact of Proteins on Existing Medications

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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to

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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to

Revolutionary Nanosensing Method Enhances Quality Control of Viral Vectors in Gene Therapy

Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can

Revolutionizing Drug Screening: The Power of Electrical Impedance Tomography for Extracellular Voltage Activation

Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
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Revolutionizing Genomics: The Future of RNA Chip Technology

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An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient. An international

Younger Generations Face Increased Cancer Risks: A Closer Look at Generations X and Millennials

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A new large study suggests incidence rates continued to rise in successively younger generations in 17 of the 34 cancer types, including breast, pancreatic, and gastric cancers. Mortality trends also increased in conjunction with the incidence of liver (female only), uterine corpus, gallbladder, testicular, and colorectal cancers. A new large study led by researchers at

Navigating the Complex Landscape of Obesity Genetics: Challenges and Opportunities

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Research on the genetics of obesity dates to the early 1920s, with many of the initial findings indicating the complexity and multifaceted nature of obesity perfectly resonating with more modern discoveries. Researchers have collected nearly a century's worth of considerations and advancements to frame their perspectives on modern research into the genetics of obesity. Research

Pushing Limits: The Fine Line Between Muscle Growth and Strength Training

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When lifting weights, do you wonder how pushing yourself to the point of failure -- where you can't do another rep -- impacts your results? New research finds that if you're aiming for muscle growth, training closer to failure might be more effective. It doesn't matter if you adjust training volume by changing sets or

This Protein Takes a Twisted Turn

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The NMDAR is involved in numerous cognitive functions including memory. Its movements are tightly coordinated like a choreographed dance routine. Scientists have now figured out how the protein performs a difficult 'Twist'-like dance move. The discovery could lead to new drug compounds that bind to NMDAR more effectively. Proteins are constantly performing a kind of

Revolutionizing Cancer Detection: How Routine Blood Tests May Enhance Diagnosis for Stomach Discomfort Sufferers

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A new study looked at data from more than 400,000 people aged 30 or older in the UK who had visited a GP due to stomach pain and more than 50,000 who had visited their GP due to bloating. The results of routine blood tests could be used to speed up cancer diagnosis among people

Harnessing AI to Unleash Exciting New Antibiotics Against Resistant Bacteria

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In a hopeful sign for demand for more safe, effective antibiotics for humans, researchers have leveraged artificial intelligence to develop a new drug that already is showing promise in animal trials. In a hopeful sign for demand for more safe, effective antibiotics for humans, researchers at The University of Texas at Austin have leveraged artificial

Unlocking Secrets of Sperm: How Non-Coding RNAs in Testes Could Reimagine Reproductive Biology

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Researchers have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had been previously estimated, indicating that lncRNAs may play a more significant role in male reproduction than previously believed. Researchers at the University of

The Surprising Resilience of Friendships in America

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American adults may typically have more friends than indicated by other recent surveys, with fewer Americans having no friends at all -- though many would like closer friendships, according to a new study. American adults may typically have more friends than indicated by other recent surveys, with fewer Americans having no friends at all --

The Impact of Social Influence on Healthier Shopping Choices: Insights from Recent Research

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A randomized trial conducted by health economists found that a bit of peer influence can nudge us to select healthier groceries. Amid the rise of chronic diseases, such as heart disease and diabetes, a novel study by Duke-NUS Medical School offers a fresh perspective on encouraging healthier grocery shopping. Despite the widespread use of colour-coded

Cultural Perspectives on Body Appreciation: A Global Exploration

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People from different cultures show both similarities and differences in how body appreciation, sociocultural pressure, and internalization of thin ideals vary, according to a new study. People from different cultures show both similarities and differences in how body appreciation, sociocultural pressure, and internalization of thin ideals vary, according to a study published July 31, 2024

Transforming Immune Cells: A Key Factor in the Success of Stem Cell Transplants for Cancer Patients

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Researchers have determined that type II innate lymphoid cells (ILC2s), a type of immune cell, can change its characteristics and functions after a cancer patient receives stem cells from a donor, thereby preventing an effective, healthy rebuilding of the immune system. This new understanding of ILC2 cells' transformational flexibility could lead to better strategies for
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