Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can
Fewer side effects, improved chances of healing: the goal of precision medicine is to provide patients with the most individualized treatment possible. This requires a precise understanding of what is happening at the cellular level. Researchers have now succeeded in mapping the interactions of 144 active substances with around 8,000 proteins. The results could help
Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can
Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can
Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
Fewer side effects, improved chances of healing: the goal of precision medicine is to provide patients with the most individualized treatment possible. This requires a precise understanding of what is happening at the cellular level. Researchers have now succeeded in mapping the interactions of 144 active substances with around 8,000 proteins. The results could help
Researchers use microscopy to chart amyloid beta's underlying structure and yield insight into neurodegenerative disease. Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases like Alzheimer's. Despite its constant stint in the limelight, however, researchers have been unable to get a good understanding of how A-beta comes together and breaks apart.
Health records and health care use show youth whose parents have been incarcerated have more physical and mental health challenges. Identifying those youth is a problem because most health systems don't have an established system for asking families about incarceration. Researcher Samantha Boch has studied the impact of incarceration on child and family health for
Cobras kill thousands of people a year worldwide and current antivenom treatment is expensive and does not effectively treat the necrosis of the flesh where the bite occurs. Using CRISPR technology, scientists have discovered a commonly available drug can stop the necrosis, potentially saving thousands of lives a year. Scientists at the University of Sydney
People's moral values could limit their uptake of lab-grown meat, a study suggests. People who say living a natural life is morally important to them are more likely to reject lab-grown meat -- also known as cultured or cultivated meat -- than those who do not, research shows. People's moral values could limit their uptake
Globally, around 2.6 million children and adolescents are currently living with HIV, the majority of them in Africa. These young people are much more likely to experience treatment failure than adults. Experts long assumed that testing for viral drug resistance could improve treatment in cases where treatment has failed. However, a research team now shows
Scientists have discovered that 'switching off' a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25 percent. Scientists at the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that 'switching off' a protein called IL-11 can significantly increase the healthy lifespan of mice by almost
Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells. This ability helps the viruses infect different species -- and
Solar cell, telescope and other optical component manufacturers may be able to design better devices more quickly with AI. Solar cell, telescope and other optical component manufacturers may be able to design better devices more quickly with AI. OptoGPT, developed by University of Michigan engineers, harnesses the computer architecture underpinning ChatGPT to work backward from
A new study shows that about two percent of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals more susceptible to viral diseases like COVID-19. The study is based on an analysis of a large collection of historical blood samples. A new study shows that about two percent of
Although devices such as standing desks have been found to alleviate physical symptoms and increase worker productivity, questions remain regarding the best use of the primary types of workstations -- stand-biased, sit-stand or traditional -- for increasing workers' physical activity and preventing health problems. To answer these questions, researchers measured the computer usage and activity
A meta-analysis of existing research shows exposure to nature, even as little as 10 minutes, could benefit those with diagnosed mental illness. Spending time in nature -- even as little as 10 minutes -- can yield short-term benefits for adults with mental illness, according to a new study published in the peer-reviewed journal Ecopsychology. The
Researchers conduct large-scale studies with diverse groups to better understand the genetic factors that influence health and disease. The Million Veteran Program (MVP), for example, includes people from various backgrounds along with their detailed health records. A new study analyzed genetic data from 635,969 veterans and 2,069 traits and identified a total of 26,049 associations
