Liver

Researchers uncovered new information about the role inflammation plays in mitigating liver fibrosis, which is associated with metabolic-associated fatty liver disease (MAFLD), one of the most common diseases in the world affecting up to 40 percent of U.S. adults. Researchers at UCLA Health uncovered new information about the role inflammation plays in mitigating liver fibrosis

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis. MASH is a consequence of poor diet and obesity and results in severe damage to the liver. In MASH, the liver becomes filled with active and rapidly multiplying T cells, which are

High-protein diets, known as 'Paleolithic diets', are popular. Using mouse models, scientists have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks. Excess protein greatly increases ammonium production, overwhelming the liver. Excess ammonium can cause neurological disorders and, in severe cases, lead to coma. These results suggest

Pet cats may be excellent animal models for the study of obesity origins and treatment in humans, a new study of feline gut microbes suggests -- and both species would likely get healthier in the research process, scientists say. Pet cats may be excellent animal models for the study of obesity origins and treatment in

Adolescents consume around two-thirds of their daily calories from ultra-processed foods (UPFs) new research has found. The study found that UPF consumption was highest among adolescents from deprived backgrounds, those of white ethnicity, and younger adolescents. Adolescents consume around two-thirds of their daily calories from ultra-processed foods (UPFs) new research from the Universities of Cambridge

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. Researchers have discovered that cells blood vessels in the liver start a 'sleep timer' that switches off immune cells. Targeting this mechanism could be a starting point for immunotherapies. In chronic hepatitis B, the liver

A new study has found a startling disparity in the frequency of liver disease for transgender individuals and highlights the need for more specialized care. Cirrhosis is chronic, progressive end-stage liver disease that occurs when scar tissue prevents the liver from functioning normally. Studies have shown that two of the leading causes of cirrhosis --

New research shows how stem cell-derived therapy, targeting treatment-resistant liver cancer through genetically modified NK cells, offers promising new avenues for immunotherapy. Researchers at University of California San Diego have found that the most common form of liver cancer -- one with a high mortality rate -- can be better targeted and treated using an

Researchers have provided new insights into the lasting effects of chronic Hepatitis C virus (HCV) infection on the immune system, even after the disease has been successfully treated. The research team has discovered that traces of 'epigenetic scars' remain in regulatory T cells and exhibit sustained inflammatory properties long after the virus is cleared from

While the liver is one of the body's most resilient organs, it is still vulnerable to the ravages of stress and aging, leading to disease, severe scarring and failure. A research team now might have found a way to turn back time and restore the liver. In experiments using mice and liver tissue from humans

A study developed a novel approach to using health care data to measure rates of liver injury since the current method of counting cases is not providing an accurate picture. The current method for assessing medication-related liver injury is not providing an accurate picture of some medications' toxicity -- or lack thereof -- to the

The flow of oxygen and nutrients to the liver, leading to the progression of fatty liver disease. This groundbreaking discovery sheds light on the mechanism behind SLD and paves the way for potential new treatments. With further research, this finding could revolutionize the way we approach and treat this increasingly prevalent and dangerous liver disease