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The Fitness Factor: Why Weight Isn’t the Whole Story

As rates of obesity, as defined by body mass index (BMI), continue to climb in the United States, so have efforts to lose weight, including a new era of weight-loss drugs. Yet a new systematic review and meta-analysis found that cardiorespiratory fitness was a stronger predictor of both cardiovascular disease and all-cause mortality than BMI.

A Breakthrough Finger Prick Test Could Revolutionize Alzheimer’s Diagnosis

A quick finger prick and a few drops of blood on a card that can be sent in regular mail. This approach could soon make Alzheimer's testing much more accessible worldwide. A quick finger prick and a few drops of blood on a card that can be sent in regular mail. This approach could soon

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The Fitness Factor: Why Weight Isn’t the Whole Story

As rates of obesity, as defined by body mass index (BMI), continue to climb in the United States, so have efforts to lose weight, including a new era of weight-loss drugs. Yet a new systematic review and meta-analysis found that cardiorespiratory fitness was a stronger predictor of both cardiovascular disease and all-cause mortality than BMI.

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The Fitness Factor: Why Weight Isn’t the Whole Story

As rates of obesity, as defined by body mass index (BMI), continue to climb in the United States, so have efforts to lose weight, including a new era of weight-loss drugs. Yet a new systematic review and meta-analysis found that cardiorespiratory fitness was a stronger predictor of both cardiovascular disease and all-cause mortality than BMI.

Beyond Cholesterol: The Hidden Lipid Contributors to Trans Fat-Induced Heart Disease

Salk scientists have tracked the flow of trans fats using mouse models to describe the molecular mechanisms that cause trans fats to promote atherosclerotic cardiovascular disease (ASCVD), explaining how industrially produced trans-unsaturated fatty acids in our food significantly promote ASCVD and encouraging lawmakers to impose regulations on the use of these fats in food. This

A Breakthrough Finger Prick Test Could Revolutionize Alzheimer’s Diagnosis

A quick finger prick and a few drops of blood on a card that can be sent in regular mail. This approach could soon make Alzheimer's testing much more accessible worldwide. A quick finger prick and a few drops of blood on a card that can be sent in regular mail. This approach could soon
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The Long-Term Life Risks Associated with Preterm Birth: A Closer Look at Adult Mortality Rates

Being born preterm is associated with an increased risk of death from birth until the third and fourth decades of life. According to a new study from researchers at Wake Forest University School of Medicine and The Hospital for Sick Children (SickKids) in Toronto, being born preterm is associated with an increased risk of death

Transforming Fiber: Researchers Revolutionize the Enjoyability of Nutrient-Dense Foods

Fiber is something that most of us get far too little of. To change that, we need to actually enjoy eating it. Food researchers have now invented a 'disguise' that solves the problem of the dry and gritty mouth feel of fibers. Fiber is something that most of us get far too little of. To

Copper Deprivation: A New Perspective on Tumor Cell Survival

While toxic in high concentrations, copper is essential to life as a trace element. Many tumors require significantly more copper than healthy cells for growth -- a possible new point of attack for cancer treatment. Medical researchers have now introduced a novel method by which copper is effectively removed from tumor cells, killing them. While

Revolutionary Alcohol-Inspired Treatment Restores Voices for Laryngeal Dystonia Sufferers

Researchers have led a clinical trial of a drug that mimics the effects of alcohol in more than 100 patients with laryngeal dystonia, a neurological condition that causes involuntary muscle spasms in the larynx and can have debilitating impacts on a person's voice. The trial was inspired by patient reports that their symptoms improved after

Harnessing AI for Accurate Depression Diagnosis: A Revolutionary Approach

Depression is one of the most common mental illnesses. As many as 280 million people worldwide are affected by this disease, which is why researchers have developed an artificial intelligence (AI) model that helps to identify depression based on both speech and brain neural activity. This multimodal approach, combining two different data sources, allows a

Future Fears: Climate Change and Air Pollution Could Claim 30 Million Lives Each Year by 2100

Mortality attributable to air pollution and extreme temperatures is a major concern, and it is expected to heighten in the future. An international research team found that, under the most probable projection, annual mortality rates linked to air pollution and extreme temperatures could reach 30 million by the end of the century. The research, based

The Surprising Connection Between Exercise and Brain Development

Exercise can have benefits at the level of neurons, through chemical and mechanical effects, researchers find. The discovery could inform exercise-related therapies for repairing damaged and deteriorating nerves. There's no doubt that exercise does a body good. Regular activity not only strengthens muscles but can bolster our bones, blood vessels, and immune system. Now, MIT

How Immune Cells Detect and Respond to Infections

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, and what is the relationship between the scale and nature of this activation and the substance being detected? In a recent study, researchers used an innovative method

Finland Launches Innovative Epilepsy Care Pathway

A new model for epilepsy care provides a streamlined, multidisciplinary approach to the diagnosis and treatment of epilepsy, and combines modern digital tools, data sharing and peer support. The Finnish epilepsy care pathway has been published in Epilepsia Open. This Finnish model for epilepsy care provides a streamlined, multidisciplinary approach to the diagnosis and treatment

Yeast Revolution: A New Era of Mass-Producing Herbal Remedies

Herbal medicine is difficult to produce on an industrial scale. A team of bioengineers have now manipulated the cellular machinery in a species of yeast so that one such molecule can now be produced in a fermenter at unprecedented concentrations. The achievement also points the way to the microbial production of other plant-derived compounds. Herbal

Enhanced Outcomes for Chemotherapy in Neuroblastoma

Blocking the METTL3 protein can increase sensitivity to chemotherapy in neuroblastoma, according to new research. The study shows how specific RNA modifications affect gene expression in the early development of neuroblastoma. Blocking the METTL3 protein can increase sensitivity to chemotherapy in neuroblastoma, according to research from the University of Gothenburg. The study shows how specific

Vitamin D Supplements: A Key to Lowering Blood Pressure in Obese Seniors

Vitamin D supplements may lower blood pressure in older people with obesity, and taking more than the Institutes of Medicine's recommended daily dose does not provide additional health benefits, according to new research. Vitamin D supplements may lower blood pressure in older people with obesity and taking more than the Institutes of Medicine's (IOM) recommended