Brain-imaging data collected from fetuses and infants has revealed a rapid surge in functional connectivity between brain regions on a global scale at birth, possibly reflecting neural processes that support the brain's ability to adapt to the external world, according to a new study. Brain-imaging data collected from fetuses and infants has revealed a rapid
Engineered proteins are critical industrial and medical applications, ranging from vaccine development to making crops or food proteins more resilient. Scientists can engineer proteins to improve upon nature, but such experiments are time- and labor-intensive. Researchers have developed an AI-based protein design tool known as EVOLVEPro, which is already showing promise for several applications and
Brain-imaging data collected from fetuses and infants has revealed a rapid surge in functional connectivity between brain regions on a global scale at birth, possibly reflecting neural processes that support the brain's ability to adapt to the external world, according to a new study. Brain-imaging data collected from fetuses and infants has revealed a rapid
Brain-imaging data collected from fetuses and infants has revealed a rapid surge in functional connectivity between brain regions on a global scale at birth, possibly reflecting neural processes that support the brain's ability to adapt to the external world, according to a new study. Brain-imaging data collected from fetuses and infants has revealed a rapid
A wearable electrical nerve stimulation device can provide relief to people experiencing the persistent pain and fatigue linked to long COVID, according to new research. A wearable electrical nerve stimulation device can provide relief to people experiencing the persistent pain and fatigue linked to long COVID, a study co-led by UCLA and Baylor College of
Engineered proteins are critical industrial and medical applications, ranging from vaccine development to making crops or food proteins more resilient. Scientists can engineer proteins to improve upon nature, but such experiments are time- and labor-intensive. Researchers have developed an AI-based protein design tool known as EVOLVEPro, which is already showing promise for several applications and
Research shows a one-third chance of restoring blood circulation during cardiac arrest, regardless of whether the medication is administered into the bloodstream or bone marrow. There is no difference in the effectiveness of the two most commonly used methods for administering medication during out-of-hospital cardiac arrest. This is shown in a large new clinical study
A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may promote lung cancer progression. A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells
Scientists have discovered the mechanism which allows the superbug Methicillin Resistant Staphylococcus aureus (MRSA) to become highly resistant to antibiotics, paving the way for new approaches to control infectious disease. Scientists have discovered the mechanism which allows the superbug Methicillin Resistant Staphylococcus aureus (MRSA) to become highly resistant to antibiotics, paving the way for new
Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- are edited by the spliceosome. The sheer number of components involved has meant the scientific feat took more than a decade to
A team of doctors and scientists have identified the cause of a rare disorder involving intellectual disability and brain malformations. The team found a link between the child's neurological symptoms and a genetic change that affects how proteins are properly folded within cells, providing the parents with a molecular diagnosis and identifying an entirely new
Scientists investigating animal viruses with potential to infect humans have identified a critical protein that could enable spillover of a family of organisms called arteriviruses. In a new study, researchers identified a protein in mammals that welcomes arteriviruses into host cells to start an infection. The team also found that an existing monoclonal antibody that
A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale. A study now identifies, for the first time, hundreds of brain proteins that explain inter-individual differences in functional connectivity and structural covariation in the human brain. A long-standing goal
Researchers have developed a computational technique that makes spatial RNA transcripts more accessible and precise, allowing them to be visualized at microscopic resolution. They say a picture is worth a thousand words. A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way
Researchers have developed a compact, wearable ultrasound device that monitors muscle activity. Attachable to the skin with an adhesive and powered by a small battery, the device wirelessly captures high-resolution images of muscle movements, enabling continuous, long-term monitoring. When worn on the rib cage, it effectively monitored diaphragm function for respiratory health assessments. When worn
A comprehensive analysis of breast cancer metastases compares various methods and affords new insights into the biology of tumors. A comprehensive analysis of breast cancer metastases compares various methods and affords new insights into the biology of tumors. Metastatic breast cancer (MBC) is the most common cancer-related cause of death in women worldwide. Despite considerable
Tumors often contain areas of oxygen-deficient tissue that frequently withstand conventional therapies. This is because the drugs applied in tumors require oxygen to be effective. An international research team has developed a novel mechanism of action that works without oxygen: polymeric incorporated nanocatalysts target the tumor tissue selectively and switch off the glutathione that the
Engineers have come up with a solution to a tricky problem: where to install charging stations for electric vehicles so they're convenient for drivers and profitable for investors. Cornell University engineers have come up with a solution to a tricky problem: where to install charging stations for electric vehicles so they're convenient for drivers and