Health

A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may promote lung cancer progression. A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells

Scientists have discovered the mechanism which allows the superbug Methicillin Resistant Staphylococcus aureus (MRSA) to become highly resistant to antibiotics, paving the way for new approaches to control infectious disease. Scientists have discovered the mechanism which allows the superbug Methicillin Resistant Staphylococcus aureus (MRSA) to become highly resistant to antibiotics, paving the way for new

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- are edited by the spliceosome. The sheer number of components involved has meant the scientific feat took more than a decade to

A team of doctors and scientists have identified the cause of a rare disorder involving intellectual disability and brain malformations. The team found a link between the child's neurological symptoms and a genetic change that affects how proteins are properly folded within cells, providing the parents with a molecular diagnosis and identifying an entirely new

Scientists investigating animal viruses with potential to infect humans have identified a critical protein that could enable spillover of a family of organisms called arteriviruses. In a new study, researchers identified a protein in mammals that welcomes arteriviruses into host cells to start an infection. The team also found that an existing monoclonal antibody that

A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale. A study now identifies, for the first time, hundreds of brain proteins that explain inter-individual differences in functional connectivity and structural covariation in the human brain. A long-standing goal

Researchers have developed a computational technique that makes spatial RNA transcripts more accessible and precise, allowing them to be visualized at microscopic resolution. They say a picture is worth a thousand words. A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way

Researchers have developed a compact, wearable ultrasound device that monitors muscle activity. Attachable to the skin with an adhesive and powered by a small battery, the device wirelessly captures high-resolution images of muscle movements, enabling continuous, long-term monitoring. When worn on the rib cage, it effectively monitored diaphragm function for respiratory health assessments. When worn

A comprehensive analysis of breast cancer metastases compares various methods and affords new insights into the biology of tumors. A comprehensive analysis of breast cancer metastases compares various methods and affords new insights into the biology of tumors. Metastatic breast cancer (MBC) is the most common cancer-related cause of death in women worldwide. Despite considerable

Tumors often contain areas of oxygen-deficient tissue that frequently withstand conventional therapies. This is because the drugs applied in tumors require oxygen to be effective. An international research team has developed a novel mechanism of action that works without oxygen: polymeric incorporated nanocatalysts target the tumor tissue selectively and switch off the glutathione that the

Engineers have come up with a solution to a tricky problem: where to install charging stations for electric vehicles so they're convenient for drivers and profitable for investors. Cornell University engineers have come up with a solution to a tricky problem: where to install charging stations for electric vehicles so they're convenient for drivers and

A research team has found that giving iron supplements to children living with human immunodeficiency virus (HIV) in sub-Saharan Africa could be an important first step in optimizing brain development. A University of Minnesota Medical School research team has found that giving iron supplements to children living with human immunodeficiency virus (HIV) in sub-Saharan Africa