Health

New research suggests older adults wait 3-6 months after a heart attack before elective noncardiac surgery to reduce the risk of serious complications like stroke or another heart attack. After a heart attack, aging adults face double or triple the risk of life-threatening complications -- like a debilitating stroke or another heart attack -- when

Treating anxiety, depression and other disorders may depend on the amygdala, a part of the brain that controls strong emotional reactions, especially fear. But a deep understanding of this structure has been lacking. Now scientists have identified new clusters of cells with differing patterns of gene expression in the amygdala of humans and non-human primates.

A new analysis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -- and the cells of a tumor's surrounding environment -- are organized, in 3D, and how that organization changes when a tumor spreads to other organs. The detailed findings offer scientists

Researchers have found a process by which the brain guards against attack by the immune system. In mice with multiple sclerosis, such 'guardian' proteins that train the immune system were drastically depleted, and replenishing them improved symptoms, according to a new study. The brain constantly engages in dialogue with the body's immune system. Such communication

New research into the long-term dynamics of transplanted stem cells in a patient's body explains how age affects stem cell survival and immune diversity, offering insights that could make transplants safer and more successful. For the first time, scientists have tracked what happens to stem cells decades after a transplant, lifting the lid on the

An international research team has investigated how nanoplastic particles deposited in the body affect the effectiveness of antibiotics. The study showed that the plastic particles not only impair the effect of the drugs, but could also promote the development of antibiotic-resistant bacteria. In a recent study, an international research team with significant involvement from MedUni

Doctors struggle to accurately predict pneumonia patients' prognoses and determine the most effective treatments. Now, by applying a sophisticated machine-learning approach to electronic health records (EHRs) of patients with pneumonia, researchers uncovered five distinct clinical states in pneumonia. Two patients being treated for pneumonia, an infection that causes difficulty breathing due to fluid-filled sacs in

Researchers designed tiny particles that can be implanted at a cancer tumor site, where they deliver two types of therapy: heat and chemotherapy. Patients with late-stage cancer often have to endure multiple rounds of different types of treatment, which can cause unwanted side effects and may not always help. In hopes of expanding the treatment

Scientists highlighted the potential for ultrasound to treat some of the more complex health conditions affecting the human brain. Ultrasound, once used almost exclusively to take images of the body, is quickly developing into a targeted therapy that can have a potentially life-changing impact on our brains, according to the authors of a new article.

Medical scientists involved in a large international study have identified new signs of kidney transplant rejection that could lead to more precise diagnosis and treatment for transplant recipients. The research examined more than 16,000 kidney transplant biopsies and found that certain results previously thought to be of questionable significance actually indicate an increased risk of

Researches made major strides toward the creation of artificial kidney tissue by demonstrating an undiscovered mechanism behind kidney development and a novel technique for culturing kidney cells, both of which could ultimately reduce the need for both dialysis and transplantation. To Alex Hughes, Assistant Professor in Bioengineering within Penn Engineering and in Cell and Developmental

Mechanical engineers designed a 3D-printed femur that could help doctors prepare for surgeries to repair bones and develop treatments for bone tumors. The study, which focused on the middle section of the bone, establishes 3D-printing parameters for a femur for use in biomechanical testing. Researchers said more studies will be needed before the technology could