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Detecting the Subtle Early Signs of Alzheimer’s Disease

People with Alzheimer's exhibit a loss of motor control along with cognitive decline, and one of the earliest signs of this decay can be spotted in involuntary eye movements known as saccades. These quick twitches of the eyes in Alzheimer's patients are often slower, less accurate, or delayed compared to those in healthy individuals. Researchers

The Impact of Golgi Stress on T-Cell Effectiveness Against Tumors

Researchers investigating ways to reduce exhaustion in cancer-fighting T-cells found that the Golgi apparatus can be used as a simple marker -- more Golgi means a more robust cell. The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core

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Detecting the Subtle Early Signs of Alzheimer’s Disease

People with Alzheimer's exhibit a loss of motor control along with cognitive decline, and one of the earliest signs of this decay can be spotted in involuntary eye movements known as saccades. These quick twitches of the eyes in Alzheimer's patients are often slower, less accurate, or delayed compared to those in healthy individuals. Researchers

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Detecting the Subtle Early Signs of Alzheimer’s Disease

People with Alzheimer's exhibit a loss of motor control along with cognitive decline, and one of the earliest signs of this decay can be spotted in involuntary eye movements known as saccades. These quick twitches of the eyes in Alzheimer's patients are often slower, less accurate, or delayed compared to those in healthy individuals. Researchers

When Your Mind Overanalyzes: The Conflict Between Instinct and Intellect

Scientists sought to better understand how humans evolved to become so skilled at thinking about what's happening in other peoples' minds. The findings could have implications for one day treating psychiatric conditions such as anxiety and depression. We've all been there. Moments after leaving a party, your brain is suddenly filled with intrusive thoughts about

The Impact of Golgi Stress on T-Cell Effectiveness Against Tumors

Researchers investigating ways to reduce exhaustion in cancer-fighting T-cells found that the Golgi apparatus can be used as a simple marker -- more Golgi means a more robust cell. The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core
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Unveiling the Diverse Fibroblast Subtypes in Skin Cancer Research

A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results are relevant for the development of novel skin cancer therapies, particularly in the field of immunotherapy. A study at MedUni Vienna's Department of Dermatology provides insights into

“Mastering Mouse Cells: Scientists Enhance Tissue Engineering Through Crowd Control Techniques”

Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs. Biologists have now characterized the influence of another important developmental driver: cell density, or how loosely or tightly cells are packed into a given space. In both computational models and laboratory experiments, the team of scientists used cell density as an

Unlocking the Brain’s Mechanism for Calming Anxious Breathing

Scientists discovered a brain circuit that allows us to regulate voluntary breathing, which connects the brain's emotional and behavioral cortical area to its automatic breathing brainstem area. The findings provide a targetable area for slowing breathing in people with anxiety, panic disorders, or PTSD, in addition to explaining the efficacy of slowed, intentional breathing in

Harnessing Biophysics to Create Innovative Vaccines for RSV and Other Respiratory Viruses

In most people, the lung-infecting pathogens known as respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) trigger mild cold-like symptoms. But in infants and seniors, these viruses can cause severe pneumonia and even death. Vaccines against both viruses, however, have been difficult to design. Now, scientists have analyzed the structure and stability of a critical

Nurturing Minds: How Creativity Camps Boost Adolescent Mental Health and Happiness

A research team found that Creativity Camp, a two-week arts intervention delivered as a day camp, had a positive impact on mental health and well-being in adolescents with depression. Published in Child Psychiatry and Human Development, a research team led by the University of Minnesota Medical School found that Creativity Camp, a two-week arts intervention

Emerging Subtypes of a Widespread Brain Disorder

Researchers have used AI tools to describe three sub-types of Chiari type-1, which will help guide clinicians to make the most effective treatment decisions for their patients. Chiari type-1 malformation is a condition in which the cerebellum extends beyond the gap in the skull where it connects to the spinal cord. Roughly 4% of the

Unmasking the True Price of Our Dietary Choices

Shifting our diets to be more sustainable can be a powerful way for each of us to address both climate change and global food insecurity, however making such adjustments at the large scales necessary to make a difference globally can be a delicate matter. Shifting our diets to be more sustainable can be a powerful

Promising New Drug Emerges for Combatting Cognitive Decline in Parkinson’s Disease

A recently published study found that a tiny protein called PNA5 appears to have a protective effect on brain cells, which could lead to treatments for the cognitive symptoms of Parkinson's disease and related disorders. A recently published study by researchers at the University of Arizona Health Sciences found that a tiny protein called PNA5

Harnessing Antibodies to Fight Age-Related Muscle Loss

As we age, our muscles atrophy. Earlier this year, researchers found that hepatocyte growth factor (HGF), a protein critical in skeletal muscle development loses its functionality due to nitration as we age. Now, the same team has developed a monoclonal antibody that blocks the nitration sites of HGF, effectively preventing the protein's age induced loss

Understanding Cellular Adaptation: The Process of Habituation in Cells

Up until recently, habituation -- a simple form of learning -- was deemed the exclusive domain of complex organisms with brains and nervous systems, such as worms, insects, birds, and mammals. But a new study offers compelling evidence that even tiny single-cell creatures such as ciliates and amoebae, as well as the cells in our

Essential Nutrients for Expecting Mothers: Are They Being Overlooked?

New research reveals startling shortfalls in dietary nutrition during pregnancy. It's generally estimated that around 10% of pregnant people struggle to meet their nutritional needs -- but the real number could be far higher, according to new research from Stevens Institute of Technology. According to a recent study published in The Journal of Nutrition, over

Unveiling the Mind: A New Roadmap for Understanding Habits

Cognitive neuroscientists have described a brand new approach to making habit change achievable and lasting. Cognitive neuroscientists in Trinity College Dublin have published new research describing a brand new approach to making habit change achievable and lasting. This innovative framework has the potential to significantly improve approaches to personal development, as well as the clinical