Groundbreaking Research Reveals Essential Process in Learning and Memory Formation
A breakthrough study sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and memory. A breakthrough study published today in the Journal of Neurosciencesheds new light on how brain cells relay critical information from their extremities to their nucleus
Unlocking the Brain’s Secrets: How Certain Neurons in Mice Can Trigger a Hibernation Mode and Alter Metabolism
A new study has identified a group of neurons that, when activated, can induce a hypometabolic state, akin to hibernation. The discovery could have far-reaching implications for conditions like obesity, cardiometabolic diseases, and even for space travel. The research team found that these neurons regulate key aspects of the brain-heart-gut axis. A team led by
Groundbreaking Research Reveals Essential Process in Learning and Memory Formation
A breakthrough study sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and memory. A breakthrough study published today in the Journal of Neurosciencesheds new light on how brain cells relay critical information from their extremities to their nucleus
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Groundbreaking Research Reveals Essential Process in Learning and Memory Formation
A breakthrough study sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and memory. A breakthrough study published today in the Journal of Neurosciencesheds new light on how brain cells relay critical information from their extremities to their nucleus
“Racing Against Nature: Can DNA Nanoparticle Motors Match the Speed of Biological Proteins?”
DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical motion by biasing the Brownian motion. The DNA-nanoparticle motor uses the 'burnt-bridge' Brownian ratchet mechanism. In this type of movement, the motor is
Unlocking the Brain’s Secrets: How Certain Neurons in Mice Can Trigger a Hibernation Mode and Alter Metabolism
A new study has identified a group of neurons that, when activated, can induce a hypometabolic state, akin to hibernation. The discovery could have far-reaching implications for conditions like obesity, cardiometabolic diseases, and even for space travel. The research team found that these neurons regulate key aspects of the brain-heart-gut axis. A team led by
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Harnessing Deep Learning to Engineer Proteins for Countering Lethal Snake Venom
New proteins not found in nature have now been designed to counteract certain highly poisonous components of snake venom. The deep learning, computational methods for developing these toxin-neutralizing proteins offer hope for creating safer, more cost-effective and more readily available therapeutics than those currently in use. Each year more than 2 million people suffer snakebites.
Breakthrough Epigenetic Strategy Offers New Hope in the Fight Against Colorectal Cancer
A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study. A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors
Unveiling the Mind: Three Psychological Profiles Shaping Aging and Brain Health
An international study has identified three psychological profiles associated with different patterns of cognitive and brain decline in aging. The study, which analyzed more than 1,000 middle-aged and older adults, shows that the specific psychological characteristics of each profile may influence the risk of developing dementia, as well as aspects such as the speed of
Unraveling the Longevity of DNA Damage: A New Perspective on Mutations
While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer. While most known types of DNA
Emerging Evidence: Red Light Therapy May Reduce Blood Clot Risks
Humans and mice exposed to long-wavelength red light had lower rates of blood clots that can cause heart attacks, lung damage and strokes, according to research led by surgeon-scientists. Humans and mice exposed to long-wavelength red light had lower rates of blood clots that can cause heart attacks, lung damage and strokes, according to research
Revolutionary Trio: Enhancing CAR-T Cancer Therapy with a New Drug Cocktail
Researchers have discovered a three-drug combination that enhances the generation of CAR-T cells, a type of cancer immunotherapy, and could improve CAR-T cell production for clinical treatments. The study emphasizes the importance of T-memory stem cells (TSCM) linked to stronger and more lasting cancer responses. The findings demonstrate the advantages of pharmacological approaches over genetic
The Impact of ICU Design on Patient Delirium: A Comprehensive Exploration
ICU delirium can be associated with a multitude of factors including underlying and acute medical conditions, pharmacologic agents or treatment regimens like surgery. Currently there is no definitive consensus on drug interventions that aid in the prevention of delirium or its treatment. While there has been some evidence that the ICU environment plays a role
Examining How Medical Marijuana Laws Influence Opioid Use Trends
A new study found no changes in opioid outcomes among the general population with the states' passage of medical and recreational marijuana laws. However, the findings also show decreases in opioid outcomes after medical marijuana laws existed among people reporting cannabis use. A new study at Columbia University Mailman School of Public Health found no
Revitalize Your Workout: Unlock Explosive Muscle Growth and Power
A team of researchers discovered that combining neuromuscular electrical stimulation with resistance training results in greater muscle mass and strength compared to resistance training alone. If building strength and muscle mass is part of your New Year's Resolution, you may want to add a new routine to your workout. Neuromuscular electrical stimulation (NMES), or electrical
Unlocking a New Approach: Combating Bladder Cancer Through Cholesterol Management
Researchers discover novel targets for bladder cancer therapeutics and demonstrate that a new combination of existing drugs, including statins, blocks tumor growth in mice. Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a lid on their growth? Previous studies showed that a
Revolutionary Development: Researchers Unveil Cutting-Edge Soft Bioelectronic Sensor Implant
Scientists describe their construction of complementary, internal, ion-gated, organic electrochemical transistors that are more amenable chemically, biologically and electronically to living tissues than rigid, silicon-based technologies. The medical device based on these transistors can function in sensitive parts of the body and conform to organ structures even as they grow. The result is a biocompatible
Holiday Gains: How College Students Turn Festive Feasts into Fitness Success!
A new study from an obesity researcher reveals that college students and older adults gain holiday weight just in different ways. With the holidays behind us, many Americans are seeing the numbers on the scale go up a pound or two. In fact, data shows that many American midlife and older adults gain 1 to