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Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build the spine and nervous system (the trunk). Scientists at the Francis Crick Institute have generated human stem cell models1 which, for the first time, contain notochord --
HomeEnvironmentEnhance Bioimplant Titanium Alloys: Tin Toughening and the Cocktail Effect

Enhance Bioimplant Titanium Alloys: Tin Toughening and the Cocktail Effect

Previous studies have shown that the addition of tin to beta-type titanium alloys enhances their strength, but the reasons for this have not been fully understood. A new research team has now identified the specific mechanisms that underlie this phenomenon. Beta(β)-type titanium (Ti) alloys are widely known for their strength, formability, and ability to withstand harsh environments. Their excellent biocompatibility also makes them suitable for a variety of medical implants and prosthetics, including joint replacements and stents. However, there are instances where a brittle omega phase can develop under certain conditions, which can affect their performance.of Sn atoms on dislocations, is the key to the strengthening of β-type Ti alloys,” said Okamoto.

Dislocations are line defects in the crystal structure of a metal, and act as the main carrier of plastic deformation. When a metal is put under stress, dislocations move, leading to material failure. But anchored Sn atoms impede the motion of dislocations, thereby increasing the material’s strength. The researchers found that the key to this phenomenon lies in the interaction between multiple elements, rather than the simple addition of Sn alone.

These findings are a significant step forward in understanding the mechanical properties of β-type Ti alloys. The researchers believe that their discovery could lead to the development of even stronger titanium alloys for a wide range of applications, from medical implants to aerospace materials.

According to Ichitsubo, the combined presence of Ti and Nb, along with the doping effect of Sn atoms, collaborates to completely prevent the formation of the harmful omega phase, demonstrating what is known as the “cocktail effect.”

Similar to expertly combining different ingredients to create a delicious cocktail, the cocktail effect in metallurgy refers to the situation where mixing multiple elemental components in a well-balanced ratio can result in properties that exceed expectations.

Ichitsubo further explained that this cocktail effect is a notable occurrence in high-entropy materials, underscoring the significance of considering interactions between multiple elements.The importance of multi-element interactions in alloy design has been emphasized by Norihiko L. Okamoto. This discovery has implications not only for biomaterials but also for alloy design in general. Understanding the precise details of strengthening β-type Ti alloys will be beneficial for improving biomedical titanium implants, which are crucial for supporting individuals with degenerative bone conditions or aging populations.