Autoimmune

Scientists have discovered that electrical currents may make Natural Killer (NK) cells -- our very own cancer-killing immune cells -- even better killers, which could have significant implications for treating some cancers. The scientists found that Tumour Treating Fields (TTF) in the laboratory (which mimic exposure of brain tumors to electric currents via a simple

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research. A simple blood test that measures the number of lymphocytes, a type of white blood

Scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine's most formidable foes. USC scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody

A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against 'inflammageing', which is widely believed to be the root cause of many age-related diseases. A study raises the exciting possibility of a protective agent that could dampen age-related inflammation and restore normal immune function in older adults.

A new study shows that about two percent of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals more susceptible to viral diseases like COVID-19. The study is based on an analysis of a large collection of historical blood samples. A new study shows that about two percent of

Biology researchers have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source -- llamas. A research team at Georgia State University has developed tiny, potent molecules that are capable of targeting hidden strains of HIV. The source? Antibody genes from llama DNA. The

Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ineffective. Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs

Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics. Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics. The study, published today as a Reviewed

Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with

In order for immune cells to effectively kill cancer cells, a triad of three cells are necessary -- a dendritic cell, a cytotoxic 'killer' T cell, and a helper T cell, researchers have found. The discovery could alter the way doctors administer immunotherapies. There's a frustrating fact about today's immunotherapies for cancer. While sometimes they

Researchers have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness. Researchers from The University of Queensland have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness. The research, led by Professor Ulrike

The study provides the basis for a phase I clinical trial in additional participants. Immune system dysregulation and elevated inflammation contribute to the development of the fatal neurodegenerative condition amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. In new research published in The FASEB Journal, repeated infusions of certain immune cells delayed ALS