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Navigating the Complex Landscape of Obesity Genetics: Challenges and Opportunities

Research on the genetics of obesity dates to the early 1920s, with many of the initial findings indicating the complexity and multifaceted nature of obesity perfectly resonating with more modern discoveries. Researchers have collected nearly a century's worth of considerations and advancements to frame their perspectives on modern research into the genetics of obesity. Research

Decoding Carbs: A Groundbreaking Glycemic Index Database for Enhanced Nutritional Understanding

Researchers create the first national glycemic index database, revealing how common foods impact health and contribute to chronic diseases. Karen Della Corte, BYU nutrition and dietetics professor, recently authored a new study, published in The American Journal of Clinical Nutrition, that developed a national glycemic index (GI) and glycemic load (GL) database to offer insights

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Navigating the Complex Landscape of Obesity Genetics: Challenges and Opportunities

Research on the genetics of obesity dates to the early 1920s, with many of the initial findings indicating the complexity and multifaceted nature of obesity perfectly resonating with more modern discoveries. Researchers have collected nearly a century's worth of considerations and advancements to frame their perspectives on modern research into the genetics of obesity. Research

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Navigating the Complex Landscape of Obesity Genetics: Challenges and Opportunities

Research on the genetics of obesity dates to the early 1920s, with many of the initial findings indicating the complexity and multifaceted nature of obesity perfectly resonating with more modern discoveries. Researchers have collected nearly a century's worth of considerations and advancements to frame their perspectives on modern research into the genetics of obesity. Research

Innovative Defense: How Pancreatic Cells in Mice Shield Themselves from Inflammation

The results of the new study could have significant implications for understanding diabetes. Researchers from the University of Cologne have revealed a mechanism protecting pancreatic β-cells, which are crucial for insulin production from inflammatory cell death. The study investigated the role of receptor-interacting protein kinase 1 (RIPK1) in regulating β-cell survival. Typically, this protein controls

Decoding Carbs: A Groundbreaking Glycemic Index Database for Enhanced Nutritional Understanding

Researchers create the first national glycemic index database, revealing how common foods impact health and contribute to chronic diseases. Karen Della Corte, BYU nutrition and dietetics professor, recently authored a new study, published in The American Journal of Clinical Nutrition, that developed a national glycemic index (GI) and glycemic load (GL) database to offer insights
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Diabetes Drug Overcomes Drug Resistance in Lung Cancer for Enhanced Chemotherapy

A medication used to treat diabetic neuropathy may make chemotherapy treatments more effective for patients with lung cancer, according to new findings. A medication used to treat diabetic neuropathy may make chemotherapy treatments more effective for patients with lung cancer, according to new findings from the University of Missouri School of Medicine published in Clinical

Paleolithic Diet Risks: What You Need to Know

High-protein diets, known as 'Paleolithic diets', are popular. Using mouse models, scientists have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks. Excess protein greatly increases ammonium production, overwhelming the liver. Excess ammonium can cause neurological disorders and, in severe cases, lead to coma. These results suggest

Fat Cats on a Diet: Understanding Obesity in Humans | Health Insights

Pet cats may be excellent animal models for the study of obesity origins and treatment in humans, a new study of feline gut microbes suggests -- and both species would likely get healthier in the research process, scientists say. Pet cats may be excellent animal models for the study of obesity origins and treatment in

Enhancing Effectiveness of Diabetes and Weight-Loss Drugs: New Research Findings

A network of proteins found in the central nervous system could be harnessed to increase the effectiveness and reduce the side effects of popular diabetes and weight-loss drugs, according to new research. A network of proteins found in the central nervous system could be harnessed to increase the effectiveness and reduce the side effects of

Reducing Dementia Risk with Metformin and Antidiabetic Drugs for Type 2 Diabetes Patients

Investigators analyzing the potential cognitive effects of antidiabetic medications in records of more than 1.5 million patients with type 2 diabetes mellitus (T2DM) found risks of dementia and Alzheimer's disease (AD) were significantly lower in patients treated with metformin and sodium glucose co-transporter-2 inhibitors (SGLT-2i) compared to other antidiabetic drugs. Investigators analyzing the potential cognitive

Distinct T-cell Signatures in Type 1 Diabetes: Key Findings at Different Stages

A study found distinct signatures in CD8-positive T cells in blood samples from children with newly diagnosed type 1 diabetes and in autoantibody-positive children who later developed type 1 diabetes. A study conducted at the University of Eastern Finland found distinct signatures in CD8-positive T cells in blood samples from children with newly diagnosed type

Revolutionary Therapy: Rejuvenating Insulin-Producing Beta Cells for New Diabetes Treatment

In preclinical studies, a team of researchers report new findings on a therapeutic combination that regenerated human insulin-producing beta cells, providing a possible new treatment for diabetes. In preclinical studies, a team of researchers from Mount Sinai Health System in New York City and City of Hope in Los Angeles report new findings on a

How to Delay Diabetes with Diet and Exercise for Better Long-Term Health

Individuals diagnosed with prediabetes can reduce their long-term risk of death and diabetes-related health complications if they delay the onset of diabetes for just four years through diet and exercise, according to new findings. Individuals diagnosed with prediabetes can reduce their long-term risk of death and diabetes-related health complications if they delay the onset of

Maximizing Heart and Kidney Benefits: The Power of Combined Diabetes Medications

New research shows combined use of sodium glucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP1-RAs) is likely to offer additional protection against heart and kidney disease in patients with diabetes. New research shows combined use of sodium glucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP1-RAs) is likely to offer

Preventing Diabetes: Slash Processed Meat Intake by One-Third to Save 350,000+ Cases in the US in 10 Years

Reducing consumption of processed meat by around one-third could prevent more than 350,000 cases of diabetes in the US over 10 years. Reducing consumption of processed meat by around one-third could prevent more than 350,000 cases of diabetes in the US over 10 years, a study suggests. Cutting US adults' processed meat intake by 30

Comprehensive Youth Diabetes Dataset and Interactive Portal for Research and Prevention Strategies

A team has developed the most comprehensive epidemiological dataset for youth diabetes and prediabetes research, derived from extensive National Health and Nutrition Examination Survey (NHANES) data collected from 1999 to 2018. The dataset, revealed through the newly launched Prediabetes/diabetes in youth ONline Dashboard (POND), aims to ignite a new wave of research into the escalating

Unlocking the Power of Proteins and Fats: Customized Nutrition and Insulin Production

When it comes to managing blood sugar levels, most people think about counting carbs. But new research shows that, for some, it may be just as important to consider the proteins and fats in their diet. The study is the first large-scale comparison of how different people produce insulin in response to each of the