Disease

A study found distinct signatures in CD8-positive T cells in blood samples from children with newly diagnosed type 1 diabetes and in autoantibody-positive children who later developed type 1 diabetes. A study conducted at the University of Eastern Finland found distinct signatures in CD8-positive T cells in blood samples from children with newly diagnosed type

Cardiovascular disease often culminates in heart failure, a hallmark of which is fibrosis, a form of tissue scarring. Cardiac fibrosis initially repairs damaged heart tissue, but it can quickly become excessive and pathological. Identifying the mechanisms behind fibrosis is a focal point in cardiovascular research, and now scientists discovered a critical genetic mechanism driving the

About a third of Canadians feel lonely, and a study shows it has a greater negative impact on memory than even social isolation, though both present a significant risk to the aging population. About a third of Canadians feel lonely, and a study from the University of Waterloo shows it has a greater negative impact

A potential new treatment for bipolar disorder (BP) that significantly shortens treatment time has emerged, following a randomized clinical trial using accelerated intermittent theta burst stimulation (aiTBS). While current theta burst stimulation (TBS) treatments can take between four and six weeks to administer, this new technique reduces treatment to five days. A potential new treatment

The study provides the basis for a phase I clinical trial in additional participants. Immune system dysregulation and elevated inflammation contribute to the development of the fatal neurodegenerative condition amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. In new research published in The FASEB Journal, repeated infusions of certain immune cells delayed ALS

Neuroprostheses allow the nervous system of a patient who has suffered an injury to connect with mechanical devices that replace paralyzed or amputated limbs. A study demonstrates in animal models how EGNITE, a derivative of graphene, allows the creation of smaller electrodes, which can interact more selectively with the nerves they stimulate, thus improving the

Researchers have revealed a novel association between chromosome 18q deletion syndrome and late-onset combined immunodeficiency (LOCID). Their finding challenges the previously held notion that 18q deletion syndrome only involves humoral immunodeficiency affecting B cells and antibody production. Moreover, the study highlights the need for regular immune function testing in 18q deletion syndrome patients for early

To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection, according to a new study. To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection

Researchers have uncovered the incidence and prevalence of the chronic allergic disorder eosinophilic esophagitis, or EoE, which can cause difficulty in swallowing as eosinophils, a type of white blood cell, build up in the esophagus. In one of the first studies of its kind in Japan, Osaka Metropolitan University-led researchers uncovered the incidence and prevalence

Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect their newborns is not associated with an increased risk of preterm birth or other poor outcomes. Infants are particularly vulnerable to the virus which can cause a serious lower respiratory illness. Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect

While H5N1 avian influenza virus taken from infected cow's milk makes mice and ferrets sick when dripped into their noses, airborne transmission of the virus between ferrets -- a common model for human transmission -- appears to be limited. These and other new findings about the strain of H5N1 circulating among North American dairy cattle

A new approach to treating the most malignant type of brain cancer -- glioblastoma -- has shown strong promise in pre-clinical settings, raising hopes of increasing current average survival rates beyond 18 months. A new approach to treating the most malignant type of brain cancer -- glioblastoma -- has shown strong promise in pre-clinical settings