Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
Companies and institutes are currently working on biotechnological processes for the production of 'dairy products' without the use of cows: In so-called precision fermentation, egg and milk proteins are produced with the help of bacteria, yeasts or other fungi. This results in foods such as milk or cheese with a familiar flavor and texture. Supporters
Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
Fewer side effects, improved chances of healing: the goal of precision medicine is to provide patients with the most individualized treatment possible. This requires a precise understanding of what is happening at the cellular level. Researchers have now succeeded in mapping the interactions of 144 active substances with around 8,000 proteins. The results could help
Companies and institutes are currently working on biotechnological processes for the production of 'dairy products' without the use of cows: In so-called precision fermentation, egg and milk proteins are produced with the help of bacteria, yeasts or other fungi. This results in foods such as milk or cheese with a familiar flavor and texture. Supporters
Adults with diabetes who meet the recommended guidelines for physical activity may offset the risk of mortality that is associated with excessive sitting time. Adults with diabetes who meet the recommended guidelines for physical activity may offset the risk of mortality that is associated with excessive sitting time, according to a new study at Columbia
Researchers have developed a model that more accurately predicts how genetics and air pollution levels causally influence disease development. Every disease is shaped by a genetic component as well as environmental factors like air pollution, climate and socioeconomic status. However, the extent to which genetics or environment plays a role in disease risk -- and
Even as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant limitation: many patients, including those whose cancer goes into full remission, eventually relapse. Researchers report on a technique with the potential to eliminate that problem. Even as they have revolutionized the treatment of certain
When seemingly healthy people receive an alert from a wearable sensor telling them they might have a respiratory virus--based on small changes in their unique heartrate, sleep and activity patterns -- what do they do? According to a new study carried out at the height of the COVID-19 pandemic, only a quarter of people follow
Peptides are gradually emerging as middle-sized therapeutic agents in addressing unmet medical needs. Compared to small-molecule drugs, peptides can target complex biological processes more precisely while generally less complex and more a cost-effective than large biological drugs like antibodies. Over 100 FDA-approved peptide drugs have been on the market since the first peptide hormone insulin
Who we choose as a partner depends in part on who we find attractive on the outside. Scientists have long wondered whether potential partners can also sense a woman's fertility, for example through subtle changes in her body odor. Researchers have now turned their attention to this question. In a new study, they not only
We all know what it's like when the penny suddenly drops. Animals too experience such moments of insight. They could prove useful for research of consciousness. We all know what it's like when the penny suddenly drops. Animals too experience such moments of insight. They could prove useful for research, according to Ekrem Dere. For
Modern cutting-edge research generates enormous amounts of data, presenting scientists with the challenge of visualizing and analyzing it. Researchers have developed a tool for visualizing large data sets. The sCIRCLE tool allows users to explore single-cell analysis data in an interactive and user-friendly way. Modern cutting-edge research generates enormous amounts of data, presenting scientists with
Lung diseases kill millions of people around the world each year. Treatment options are limited, and animal models for studying these illnesses and experimental medications are inadequate. Now, researchers describe their success in creating a mucus-based bioink for 3D printing lung tissue. This advance could one day help study and treat chronic lung conditions. Lung
Remote and hybrid working may be great for employees' work-life balance, but it may be stifling innovation, according to new research. Remote and hybrid working may be great for employees' work-life balance, but it may be stifling innovation, according to new research. The study, led by University of Essex and University of Chicago economists, found
The Childbirth Experience Questionnaire (CEQ2) was used to investigate how medical interventions influence the individual birth experience. The overall experience was rated positively. In a recent study by researchers from the universities of Cologne and Düsseldorf as well as University Hospital Bonn, mothers across Germany were asked how they rated their experiences of 'own capacity'
Substituting amines with phosphonium-based cations could greatly improve the performance of mRNA-loaded polymeric micelles, report scientists. By adopting this innovative strategy, they managed to enhance the stability and mRNA-delivery capabilities of micelle nanocarriers into tumor tissue in vivo. Their results hint at the importance of exploring other cations besides amines in mRNA drug delivery and