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Unraveling the Genetic Similarities: Humans and Baker’s Yeast in DNA Replication

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to

Nasal Vaccine for COVID-19 Shows Promise in Stopping Transmission, Animal Research Reveals

A nasal COVID-19 vaccine blocks transmission of the virus, according to an animal study. The findings suggest that vaccines delivered directly to the nose or mouth could play a critical role in containing the spread of respiratory infections. The lightning-fast development of COVID-19 vaccines just months after the virus appeared was a triumph of modern

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Unraveling the Genetic Similarities: Humans and Baker’s Yeast in DNA Replication

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to

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Unraveling the Genetic Similarities: Humans and Baker’s Yeast in DNA Replication

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to

The Next Generation of Cheese: Embracing Animal-Free Innovations

Companies and institutes are currently working on biotechnological processes for the production of 'dairy products' without the use of cows: In so-called precision fermentation, egg and milk proteins are produced with the help of bacteria, yeasts or other fungi. This results in foods such as milk or cheese with a familiar flavor and texture. Supporters

Nasal Vaccine for COVID-19 Shows Promise in Stopping Transmission, Animal Research Reveals

A nasal COVID-19 vaccine blocks transmission of the virus, according to an animal study. The findings suggest that vaccines delivered directly to the nose or mouth could play a critical role in containing the spread of respiratory infections. The lightning-fast development of COVID-19 vaccines just months after the virus appeared was a triumph of modern
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Discovering the Key Protein Behind Shingles Virus Spread: Insights from Scientists

Scientists have discovered a new evasion strategy used by the varicella zoster virus, which causes chickenpox and shingles, that may allow it to affect tissues far from the original site of infection. Scientists at the University of Colorado Anschutz Medical Campus have discovered a new evasion strategy used by the varicella zoster virus, which causes

How Evolution Tamed a Deadly Virus: Insights and Ongoing Concerns

Over the last century, a once-deadly mosquito-borne virus has evolved so that it no longer sickens humans. New research shows that changes in the virus's ability to target human cells paralleled the decline in illness and death. The findings offer important lessons in virology that may help guide better preparedness for future outbreaks of other

Discover How a Human-Infecting Parasite Creates Sterile Soldiers Like Ants and Termites

New research finds a tiny freshwater parasite known to cause health problems in humans defends its colonies with a class of soldiers that cannot reproduce. The discovery vaults this species of parasitic flatworm into the ranks of complex animal societies such as ants, bees and termites, which also have distinct classes of workers and soldiers

Discovering Element 116: A Breakthrough Method for Creating Heavier Atoms

Researchers have successfully made super-heavy element 116 using a beam of titanium-50. That milestone sets the team up to attempt making the heaviest element yet: 120. Scientists at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) are credited in the discovery of 16 of the 118 known elements. Now they've completed the crucial

Breakthrough Mouse Model for Late-Onset Alzheimer’s: Paving the Way for New Treatments

Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research. Mice don't get Alzheimer's -- and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments. Now, researchers at The

Gene Misbehavior: Uncovering Its Widespread Impact in Healthy Individuals

New insights into the prevalence and mechanisms of gene misexpression in a healthy population could help in diagnosing and developing treatments for complex diseases. Scientists have uncovered that 'gene misbehaviour' -- where genes are active when they were expected to be switched off -- is a surprisingly common phenomenon in the healthy human population. The

New Study Reveals Mammal-to-Mammal Avian Flu Transmission: Key Insights & Implications

A new study provides evidence that a spillover of avian influenza from birds to dairy cattle across several U.S. states has now led to mammal-to-mammal transmission -- between cows and from cows to cats and a raccoon. A new Cornell University study provides evidence that a spillover of avian influenza from birds to dairy cattle

Unintended Consequences of Malaria Success: Exploring the Unforeseen Impacts

The insecticide-treated bed nets and insecticide sprays that were so effective in preventing mosquito bites -- and therefore malaria -- are increasingly viewed as the causes of household pest resurgence after pests became resistant to pesticides, according to a new article. For decades, insecticide-treated bed nets and indoor insecticide spraying regimens have been important --

AI-Powered Robotics: Training Dogs to Respond to Their Masters

An international collaboration seeks to innovate the future of how a mechanical man's best friend interacts with its owner, using a combination of AI and edge computing called edge intelligence. The overarching project goal is to make the dog come 'alive' by adapting wearable-based sensing devices that can detect physiological and emotional stimuli inherent to

Exploring the Link: How Mass Layoffs May Lead to Increased Data Breaches

A research team has been exploring how mass layoffs and data breaches could be connected. Their theory: since layoffs create conditions where disgruntled employees face added stress or job insecurity, they are more likely to engage in risky behaviors that heighten the company's vulnerability to data breaches. A research team led by faculty from Binghamton

Revolutionary Foldable Pouch Actuator Enhances Finger Extension in Soft Rehabilitation Gloves

Hand rehabilitation research has markedly benefited from the introduction of soft actuators in gloves. However, existing soft rehabilitation glove designs have several limitations in finger movements. In this regard, researchers recently succeeded in adding finger straightening or extension to soft rehabilitation gloves through a novel foldable pouch actuator without compromising the already existing functionality of

Unveiling Amyloid Architecture: Insights into Structure and Impact on Health

Researchers use microscopy to chart amyloid beta's underlying structure and yield insight into neurodegenerative disease. Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases like Alzheimer's. Despite its constant stint in the limelight, however, researchers have been unable to get a good understanding of how A-beta comes together and breaks apart.