Cirrhosis is a severe liver disease caused by scar tissue hindering normal liver function. Research shows that transgender individuals face increased risk factors like alcohol use disorder and viral hepatitis, raising concerns about higher cirrhosis rates in this community.
A recent study by Keck Medicine of USC, published in The American Journal of Gastroenterology, reveals that transgender adults are twice as likely to have cirrhosis compared to cisgender adults. This highlights the urgent need for better care and support for transgender individuals.
The study, led by Dr. Brian P. Lee, aimed to provide evidence-based guidance for healthcare professionals to improve liver health outcomes for transgender patients.
Aside from the higher prevalence of cirrhosis in transgender adults, the study also found that a majority of them with cirrhosis experienced anxiety and/or depression, in contrast to cisgender patients.
Alcohol emerged as the primary cause of cirrhosis in transgender individuals, accounting for about 60% of cases, compared to around 50% in cisgender adults.
Additionally, transgender patients with cirrhosis tended to be younger, had higher rates of viral hepatitis, and were more likely to have HIV/AIDS than cisgender patients.
Possible Factors Contributing to the Disparity
Dr. Lee suggests that higher rates of depression and anxiety among transgender individuals may lead to increased alcohol use, potentially contributing to higher cirrhosis rates. The elevated prevalence of HIV/AIDS in this group could also play a role in liver disease progression.
Dr. Jeffrey Kahn speculates that limited access to quality healthcare may further exacerbate these disparities.
The study also examined the five-year outcomes for transgender and cisgender patients with cirrhosis and found that despite differences in initial care, the long-term outcomes were similar.
Study authors utilized data from a national database to compare incidences of cirrhosis, causes of the disease, and mental health conditions among transgender and cisgender adults.
Dr. Lee and Dr. Kahn hope that this study prompts further research and encourages healthcare providers to offer tailored care for transgender patients, including regular liver screenings and mental health support.
Keck Medicine’s Support for Transgender Health
Keck Medicine established the USC Gender-Affirming Care Program, offering comprehensive healthcare services for transgender individuals. The program covers preventive care, hormone therapy, and surgeries, delivered by a multidisciplinary team of experts.
Keck Medicine facilities have been recognized as ‘LGBTQ+ Healthcare Equality Leaders’ multiple times in recent years, underscoring their commitment to providing inclusive care for LGBTQ+ patients, visitors, and staff.
