Disease

For the first time, scientists have found that sleep can be detected by patterns of neuronal activity just milliseconds long, 1000 times shorter than a second, revealing a new way to study and understand the basic brain wave patterns that govern consciousness. Sleep and wake: they're totally distinct states of being that define the boundaries

Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics. Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics. The study, published today as a Reviewed

A new, large study confirms earlier findings that children with an autistic sibling have a 20% chance of being autistic themselves. Siblings of autistic children have a 20% chance of being autistic themselves -- about seven times higher than the rate in infants with no autistic siblings. That's the key finding of a new paper

Monitoring of heart rate and physical activity using consumer wearable devices was found to have clinical value for comparing the response to two treatments for atrial fibrillation and heart failure. Monitoring of heart rate and physical activity using consumer wearable devices was found to have clinical value for comparing the response to two treatments for

It's been long established that certain men become aggressive when they see their manhood as being threatened. When does this behavior emerge during development --a nd why? A new study shows that adolescent boys may also respond aggressively when they believe their masculinity is under threat -- especially boys growing up in environments with rigid

Early exposure to antibiotics can trigger long term susceptibility to asthma, according to new research. Importantly the research team isolated a molecule produced by gut bacteria that in the future could potentially be trialed as a simple treatment, in the form of a dietary supplement, for children at risk of asthma to prevent them developing

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets may help to dissolve aggregated protein. The study deepens our understanding of neurodegenerative diseases linked to protein aggregation and could help develop new therapies. Liquid-liquid phase separation

Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with

In order for immune cells to effectively kill cancer cells, a triad of three cells are necessary -- a dendritic cell, a cytotoxic 'killer' T cell, and a helper T cell, researchers have found. The discovery could alter the way doctors administer immunotherapies. There's a frustrating fact about today's immunotherapies for cancer. While sometimes they

Researchers reveal how a gene called SH2B1 works in the brain to regulate food intake. Obesity is a complicated condition, caused by a combination of genetics, the food environment, behavior, and other factors. For millennia, getting enough food to survive and thrive was difficult. For most people, it's now as easy as opening a refrigerator.

Propofol, a drug commonly used for general anesthesia, induces unconsciousness by disrupting the brain's normal balance between stability and excitability. Propofol, a drug commonly used for general anesthesia, derails the brain's normal balance between stability and excitability. There are many drugs that anesthesiologists can use to induce unconsciousness in patients. Exactly how these drugs cause

A recent study identified beta frequency neural activity in the anterior cingulate cortex (ACC) of the brain's frontal lobe as the key neural signature underlying processes associated with recognizing rewards and determining subsequent choices and, thus, shaping future behaviors. As parents, teachers and pet owners can attest, rewards play a huge role in shaping behaviors