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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to
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Revolutionary Nanosensing Method Enhances Quality Control of Viral Vectors in Gene Therapy

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Revolutionizing Drug Screening: The Power of Electrical Impedance Tomography for Extracellular Voltage Activation

Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
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Unlocking Precision Medicine: The Hidden Impact of Proteins on Existing Medications

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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to

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First-Ever Discovery of a Human Odorant Receptor for Geosmin Unveiled

Geosmin is a volatile compound of microbial origin with a distinct 'earthy' to 'musty' odor that can affect the quality of water and food. A research team has now identified and characterized the human odorant receptor for geosmin for the first time. Geosmin is a volatile compound of microbial origin with a distinct "earthy" to

Revolutionary Nanosensing Method Enhances Quality Control of Viral Vectors in Gene Therapy

Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can

Revolutionizing Drug Screening: The Power of Electrical Impedance Tomography for Extracellular Voltage Activation

Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving
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Uncovering the Brain’s Role in Oxycodone Relapse: New Research Findings

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Even years after they have recovered, a person who once struggled with alcohol or opioid addiction can relapse--and that relapse is more likely to occur during particularly stressful times. Now, scientists have identified an area of the brain that plays a key role in stress-induced oxycodone relapse. Their findings explain why the drug suvorexant, which

Post-Surgery Opioid Use: Impact on Youth and Recovery

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A multi-institutional study found that 1 in 6 youths fill an opioid prescription prior to surgery, and 3% of patients were still filling opioid prescriptions three to six months after surgery, indicating persistent opioid use and possible opioid dependence. The study underscores that more guidance is needed to steer clinicians away from prescribing opioids when

Promising New Co-STAR Receptor Shows Potential in Cancer Treatment: Laboratory Study Reveals

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Using genetic engineering techniques, investigators designed a novel type of cell to recognize and fight cancer. Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center, the Lustgarten Laboratory and Bloomberg~Kimmel Institute for Cancer Immunotherapy have designed a novel type of cell to recognize and fight cancer. To produce

Young People’s Perspective on Artificial Intelligence in Healthcare: A Valuable Tool for the Future

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Children and young people are generally positive about artificial intelligence (AI) and think it should be used in modern healthcare. Children and young people are generally positive about artificial intelligence (AI) and think it should be used in modern healthcare, finds the first-of-its-kind survey led by UCL and Great Ormond Street Hospital (GOSH). The national

Advanced Fall Detection Methods for Older Adults Revealed: Improve Home Safety

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When older adults fall at home, every second counts -- especially when they are alone. New research aims to cut reaction times with a human action recognition (HAR) algorithm that uses local computing power to analyze sensor data and detect abnormal movements without transmitting to a processing center offsite. When older adults fall at home

Revolutionizing Digital Pathology with Customized AI Tools | Research Breakthrough

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Scientists developed and tested new artificial intelligence (AI) tools tailored to digital pathology--a rapidly growing field that uses high-resolution digital images created from tissue samples to help diagnose disease and guide treatment. Scientists from Weill Cornell Medicine and the Dana-Farber Cancer Institute in Boston have developed and tested new artificial intelligence (AI) tools tailored to

New Period Product Revolutionizes Women’s Health: Discover the Latest Advancements

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Researchers have created an eco-friendly, blood absorbent biomaterial that improves the performance of menstrual products by minimizing blood leakage and spilling, while also helping prevent infection. Bryan Hsu is tackling an area of research that has long been neglected -- menstrual products. "It's something that people don't feel comfortable talking about, and that's maybe an

Rising Incidence of EoE: Large-Scale Analysis Confirms Chronic Allergic Disorder Trend in Japan

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Researchers have uncovered the incidence and prevalence of the chronic allergic disorder eosinophilic esophagitis, or EoE, which can cause difficulty in swallowing as eosinophils, a type of white blood cell, build up in the esophagus. In one of the first studies of its kind in Japan, Osaka Metropolitan University-led researchers uncovered the incidence and prevalence

Unlocking Cell Secrets: Exploring the Atlas of Proteins

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Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design. Scientists at the University of Cambridge have developed an atlas of proteins describing how they behave inside human cells. This tool could be used to search for the origins of diseases which are related to proteins misbehaving such

Uncovering the Risks: H5N1 and Raw Cow’s Milk Transmission in Mammals

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While H5N1 avian influenza virus taken from infected cow's milk makes mice and ferrets sick when dripped into their noses, airborne transmission of the virus between ferrets -- a common model for human transmission -- appears to be limited. These and other new findings about the strain of H5N1 circulating among North American dairy cattle

Unlocking the Power of Adult Neurogenesis: How the Brain Organ Influences Growth

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Research found the choroid plexus and cerebrospinal fluid play a key role in maintaining a pool of newly born neurons to repair the adult brain after injury. University of Cincinnati researchers have pioneered an animal model that sheds light on the role an understudied organ in the brain has in repairing damage caused by stroke.

Unlocking Creativity in Infants: New Research Reveals Startling Insights

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New research indicates that babies can begin grasping complex language and ideas. Infants less than a year old can combine simple concepts into complex ideas, showing that creativity begins in babyhood. According to new research at the University of Birmingham, in the UK, and Central European University, in Austria and Hungary, babies are not only
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