Spinal Cord

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies of so-called organoids: Laboratory-grown tissue cultures that can

Neuroscientists have used a nanosized sensor to record spinal cord neurons in free-moving mice, a feat that could lead to the development of better treatments for spinal cord disease and injury. Implantable technologies have significantly improved our ability to study and even modulate the activity of neurons in the brain, but neurons in the spinal

Scientists have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida. A group of scientists at UCL have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken

The study provides the basis for a phase I clinical trial in additional participants. Immune system dysregulation and elevated inflammation contribute to the development of the fatal neurodegenerative condition amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. In new research published in The FASEB Journal, repeated infusions of certain immune cells delayed ALS

Research found a self-guided smartphone-based behavioral therapy led to significant improvements for patients with fibromyalgia. New research led by the University of Cincinnati and Swing Therapeutics found that a self-guided smartphone-based behavioral therapy led to significant improvements for patients with fibromyalgia. The multicenter, randomized controlled trial tested Stanza, a smartphone app that delivers acceptance and

Moderate levels of physical activity and fitness may be linked to a reduced risk of amyotrophic lateral sclerosis (ALS) later in life, according to a new study. The study only found an association between physical activity and risk of ALS in male participants, not female participants. Moderate levels of physical activity and fitness may be

And cellular interactions that underlie paralysis. This groundbreaking project promises to revolutionize the development of new treatments and therapies for spinal cord injuries, offering hope to millions of individuals worldwide. The open-source nature of 'Tabulae Paralytica' ensures that this invaluable data is accessible to researchers and clinicians around the globe, accelerating progress towards a cure for paralysis

Autonomic reflexes can become overactive or dysfunctional after a spinal cord injury, leading to a range of issues such as rapid heartbeat, high blood pressure, and breathing difficulties. The new research pinpointed a specific cellular target that could be manipulated to regulate these autonomic reflexes, offering hope for improved treatment and management of spinal cord injury-related complications. This breakthrough has the potential to significantly enhance the lives of individuals living with spinal cord injuries by addressing the underlying causes of autonomic dysfunction

Era in the fight against this aggressive disease. The innovative use of ultrasound technology to deliver targeted treatment directly to the brain offers hope for improved outcomes and prolonged survival for patients with glioblastoma. This groundbreaking approach represents a significant advancement in the field of cancer treatment and demonstrates the potential to revolutionize the way we combat brain tumors

St. Louis, they are able to analyze data from activity trackers and mobile health apps to predict recovery progress following lumbar spine surgery. This innovative approach offers a more precise and personalized way to assess patient outcomes, potentially leading to improved patient care and recovery. By harnessing the power of artificial intelligence and mobile health technology, researchers are breaking new ground in the field of surgical outcome prediction

Shows, repairs damaged discs in the spine and lowers pain symptoms in mice. This groundbreaking research offers hope for a non-invasive, targeted treatment for one of the most common sources of back pain. The use of naturally derived nanocarriers is a distinct and innovative approach, signaling a potential shift in the way we address this debilitating condition. With its potential to revolutionize back pain treatment, this gene therapy has the power to change the lives of millions suffering from disc-related back pain

Recently discovered that a chromosomal microdeletion may be linked to the development of spina bifida, shedding light on the causes of this common nervous system disorder. This finding highlights the importance of early detection and prevention, with folic acid emerging as a key preventive measure. Understanding the genetic factors involved in spina bifida can lead to more effective treatments and interventions, offering hope for the millions of people affected by this condition worldwide